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Table 1 Basic information of rats

From: Finerenone attenuates myocardial apoptosis, metabolic disturbance and myocardial fibrosis in type 2 diabetes mellitus

 

Control

DM

DM + Finerenone

TC (mmol/L)

1.78 ± 0.28

2.38 ± 0.32*

3.31 ± 1.51

HDL-C (mmol/L)

1.18 ± 0.21

0.98 ± 0.22

1.01 ± 0.39

LDL-C (mmol/L)

0.22 ± 0.06

0.75 ± 0.38*

1.24 ± 0.91

TG (mmol/L)

0.92 ± 0.31

3.29 ± 1.22*

4.57 ± 3.31

FFA (umol/dL)

25.88 ± 6.15

50.72 ± 12.16*

70.55 ± 25.88

GLU (mmol/L)

8.6 ± 1.67

23.47 ± 2.17*

25.07 ± 0.85

ALD (pg/mL)

246.45 ± 86.22

219.34 ± 47.17

262.95 ± 18.8

Weight(g)

651.33 ± 91.11

465.17 ± 54.84

483.83 ± 30.87

HW(g)

2.24 ± 0.27

2.08 ± 0.11

2.25 ± 0.3

HW/Weight (mg/g)

3.45 ± 0.23

4.5 ± 0.32*

4.63 ± 0.44

  1. TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein Cholesterol; TG, total triglyceride; FFA, free fatty acids; GLU, glucose; ALD, aldosterone; HW, heart weight
  2. *P < 0.05 compared with the control group