Fig. 7From: Finerenone attenuates myocardial apoptosis, metabolic disturbance and myocardial fibrosis in type 2 diabetes mellitusPotential protective effects of finerenone in T2DM hearts. Finerenone down-regulates the expression of CD36 on the cell membrane surface, thereby reducing lipid uptake and ROS generation. At the same time, finerenone can regulate the TNFα/TNFR1/CASPASE8 pathway, reduce the apoptosis of cardiomyocytes, and protect the myocardiumBack to article page