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Fig. 5 | Diabetology & Metabolic Syndrome

Fig. 5

From: Finerenone attenuates myocardial apoptosis, metabolic disturbance and myocardial fibrosis in type 2 diabetes mellitus

Fig. 5

Finerenone reduces PPARγ and CD36 expression and reduces ROS generation under high glucose and high fatty acid stimulation in neonatal rat cardiomyocytes. A Representative images of the Western blot of Cleaved-Casp3, BAX and BCL-2 in NRCMs with the corresponding analysis. B The production of ROS with the corresponding analysis. *P < 0.05 compared with NC; #P < 0.05 compared with HF + HG; Data are means ± SD

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