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Fig. 2 | Diabetology & Metabolic Syndrome

Fig. 2

From: Finerenone attenuates myocardial apoptosis, metabolic disturbance and myocardial fibrosis in type 2 diabetes mellitus

Fig. 2

Finerenone attenuates myocardial fibrosis and apoptosis in the heart of diabetic rats. A Masson’s trichrome staining of myocardial mesenchyme and peripheral vessel. B Representative images of the Western blot of collagen I and collagen III, with the corresponding analysis. C Cell apoptosis as determined by TUNEL assay with the corresponding analysis: apoptosis cell stained red; nuclei stained blue with DAPI. D Representative images of the Western blot of Cleaved-Casp3, BAX and BCL-2 with the corresponding analysis. *P < 0.05 compared with control; #P < 0.05 compared with DM; Data are means ± SD

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