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Fig. 1 | Diabetology & Metabolic Syndrome

Fig. 1

From: Finerenone attenuates myocardial apoptosis, metabolic disturbance and myocardial fibrosis in type 2 diabetes mellitus

Fig. 1

Finerenone attenuates left ventricular remodeling and improves cardiac function in diabetic rats. A General and heart morphology photos of rats. B HE staining of heart. B1 HE staining of cross shaft of musculi papillares in heart. B2 Representative HE staining of longitudinal left ventricular (LV) sections. B3 Representative HE staining of LV transverse sections. C Quantitative analysis of the cardiomyocyte diameter in heart tissue. D Representative images of 2D echocardiograms (D1), M‐mode echocardiograms (D2), Pulse‐wave Doppler echocardiograms of mitral inflow (D3), tissue Doppler echocardiograms (D4). E Assessment of cardiac function, including left ventricular ejection fraction (LVEF), fractional shortening (FS), early to late mitral diastolic blood ratio (E/A), and diastolic mitral annular velocity ratio (E′/A′). *P < 0.05 compared with control; #P < 0.05 compared with DM; Data are means ± SD

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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