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Table 3 Mean, Inter Quartile Range (IQR), and 95% Confidence Interval (95%CI) of the Characteristics of the participants at the initial and the end of the intervention, the variation of the variables during the intervention, and comparison of the parameters between the groups after the intervention

From: Probiotics for glycemic and lipid profile control of the pre-diabetic patients: a randomized, double-blinded, placebo-controlled clinical trial study

Variable

Group (Before Intervention) Median (IQR)

P-value

Group (After Intervention) Median (IQR)

P-value

Between groups variations Mean difference 95% CI

P-value

P-value (comparison of the groups after intervention)

Placebo

Intervention

Placebo

Intervention

Placebo

Intervention

Weight (kg)

85.0 (69–100)

74.0 (69–92)

0.417b

80 (68–98)

72 (68–90)

0.503b

− 3.35 (− 4.58, − 11.28)

0.774b

 < 0.001d

 < 0.001d

SBP (mmHg)

120 (120–130)

120 (120–130)

0.787b

125 (120–130)

125 (125–130)

0.251b

2.15 (− 1.30, − 5.60)

0.674b

0.755d

0.459c

DBP (mmHg)

80 (75–85)

80 (75–90)

0.755b

80 (75–85)

80 (75–85)

0.990b

0.89 (− 3.65, − 5.43)

0.901b

0.819d

0.961d

FBS (mg/dL)

107 (104–115)

107 (104–112)

0.897b

95 (88–100)

96 (89–102)

0.495b

1.06 (− 3.70, − 5.82)

0.764b

 < 0.001d

 < 0.001d

HbA1C (%)

5.80 (4.8–6.1)

5.80 (5.0–5.9)

0.595b

5.4 (4.8–5.9)

5.4 (4.7–5.8)

0.484b

− 0.2 (− 0.19, 0.59)

0.972*

0.133c

0.035c

Insulin level (µIU/mL)

12.2 (6.8–27.1)

11 (7.6–18.3)

0.601b

15.5 (6–25)

15.5 (8.1–25)

0.796a

0.21 (− 12.20, 12.62)

0.470b

0.451d

0.041d

HOMA-IR

3.24 (1.91–7.30)

3.15 (1.93–4.88)

0.557b

3.86 (1.51–5.98)

3.86 (1.82–5.98)

0.747b

0.16 (− 2.81, 3.13)

0.347b

 > 0.999d

0.235d

TG(mg/dL)

144 (105–173)

148 (130–173)

0.773a

110 (84–141)

117 (91–144)

0.597b

15.49 (− 16.13, 47.11)

0.972b

0.004c

0.004c

LDL(mg/dL)

114 (91–147)

112 (91–145)

0.724a

99 (84–128)

96 (84–128)

0.906b

-2.25 (− 12.05, 16.55)

0.823b

0.008c

0.016c

HDL(mg/dL)

46 (40–48)

46 (39–49)

0.846b

50 (43–54)

49 (42–55)

0.846b

0.72 (− 2.68, 4.12)

0.948b

0.005d

0.001d

  1. aindependent T-test
  2. bMann-Whitney test
  3. cpaired t-test
  4. dWilcoxon statistical test