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Table 2 Mean and Standard Deviation (SD) of the Characteristics of the participants at the initial and the end of the intervention, the variation of the variables during the intervention, and comparison of the parameters between the groups after the intervention

From: Probiotics for glycemic and lipid profile control of the pre-diabetic patients: a randomized, double-blinded, placebo-controlled clinical trial study

Variable

Group

(Before Intervention)

Mean ± SD

P-value

Group

(After Intervention)

Mean ± SD

P-value

Variations

P-value

P-value

(comparison of the groups after intervention)

Placebo

Intervention

Placebo

Intervention

Placebo

Intervention

Placebo

Intervention

Weight (kg)

85.40 ± 16.59

81.94 ± 16.81

0.417b

82.69 ± 16.42

79.34 ± 16.81

0.503b

− 2.71 ± 2.33

− 2.60 ± 2.56

0.774b

 < 0.001d

 < 0.001d

SBP (mmHg)

123.86 ± 10.65

125.29 ± 12.48

0.787b

124.71 ± 7.76

126.86 ± 6.68

0.251b

 + 0.86 ± 11.08

 + 1.57 ± 12.41

0.674b

0.755d

0.459c

DBP (mmHg)

80.71 ± 7.39

81.57 ± 8.38

0.755b

81.11 ± 7.55

82 ± 11.13

0.990b

 + 0.40 ± 10.25

 + 2.71 ± 2.33

0.901b

0.819d

0.961d

FBS (mg/dL)

109.17 ± 6.90

108.73 ± 6.72

0.897b

95.11 ± 10.55

96.17 ± 9.39

0.495b

− 14.06 ± 10.18

-12.66 ± 10.42

0.764b

 < 0.001d

 < 0.001d

HbA1C (%)

5.69 ± 0.88

5.58 ± 0.65

0.595b

5.48 ± 0.85

5.28 ± 0.78

0.484b

− 0.21 ± 0.82

− 0.29 ± 0.79

0.972a

0.133c

0.035c

Insulin level (µIU/mL)

15.73 ± 11.03

13.67 ± 9.30

0.601b

22.14 ± 26.20

22.35 ± 25.82

0.796a

 + 6.41 ± 30.68

 + 8.68 ± 25.78

0.470b

0.451d

0.041d

HOMA-IR

4.25 ± 3

3.64 ± 2.41

0.557b

5.18 ± 6.24

5.34 ± 6.20

0.747b

 + 0.92 ± 7.54

 + 1.71 ± 6.18

0.347b

 > 0.999d

0.235d

TG (mg/dL)

146.31 ± 50.54

147.94 ± 40.82

0.773a

117.40 ± 42.23

132.89 ± 83.69

0.597b

− 28.91 ± 55

− 15.06 ± 95.71

0.972b

0.004c

0.004c

LDL(mg/dL)

121.09 ± 37.71

117.29 ± 37.28

0.724a

104.74 ± 30.14

102.49 ± 29.80

0.906b

− 16.34 ± 34.51

− 14.80 ± 34.55

0.823b

0.008c

0.016c

HDL(mg/dL)

45.54 ± 8.54

44.66 ± 6.49

0.846b

49.26 ± 7.58

48.54 ± 6.63

0.846b

 + 3.71 ± 7.39

 + 3.89 ± 7.08

0.948b

0.005d

0.001d

  1. aindependent T-test /
  2. bMann-Whitney test /
  3. cpaired t-test /
  4. dWilcoxon statistical test