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Table 2 Adjusted mean values of lung function parameters in the study groups stratified by metabolic health and insulin resistance

From: The impact of insulin resistance on the association between metabolic syndrome and lung function: the Kangbuk Samsung Health Study

 

Category

p value by ANCOVA

Adjusted p valuea

MH

(n = 56,3111)

(49.3%)

MS without IR

(n = 40,255)

(35.3%)

MS with IR

(n = 17,577)

(15.4%)

MH

vs.

MS without IR

MH

vs.

MS with IR

MS without IR vs.

MS with IR

FEV1 (L)

3.372 ± 0.002

3.351 ± 0.003

3.288 ± 0.004

< 0.001

< 0.001

< 0.001

< 0.001

FEV1%

98.242 ± 0.059

98.178 ± 0.065

96.950 ± 0.107

< 0.001

1.000

< 0.001

< 0.001

FVC (L)

4.104 ± 0.003

4.084 ± 0.003

3.978 ± 0.005

< 0.001

< 0.001

< 0.001

< 0.001

FVC%

98.571 ± 0.058

98.645 ± 0.063

96.832 ± 0.105

< 0.001

1.000

< 0.001

< 0.001

FEV1(L)/FVC (L) ratio

0.8253 ± 0.0003

0.8247 ± 0.0003

0.8307 ± 0.0005

< 0.001

0.711

< 0.001

< 0.001

  1. Data are presented as adjusted mean ± standard error. The multivariable model was adjusted for age, sex, center, and continuous variables with p < 0.05 in univariate analyses, comprising BMI, smoking (pack-years), alcohol consumption (g/day), moderate physical activity frequency (times/week), systolic blood pressure, glucose, HbA1c, insulin, lipid profiles, liver enzymes, creatinine, and high-sensitivity C-reactive protein
  2. aAdjusted p value using the Bonferroni correction
  3. FEV1% = percent predicted forced expiratory volume in 1 s; FVC% = percent predicted forced vital capacity; IR = insulin resistance; MH = metabolically healthy; MS = metabolic syndrome
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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