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Table 2 Changes of left ventricular function and myocardial glucose metabolism in diabetic mice

From: Dynamic evolution and mechanism of myocardial glucose metabolism in different functional phenotypes of diabetic cardiomyopathy — a study based on 18 F-FDG microPET myocardial metabolic imaging

 

FBG (mmol/L)

MRglu (µmol/min/100 g)

Ki (ml/min/g)

SUV

Control (n = 8)

7.0 ± 2.0

30.2 ± 16.3

0.044 ± 0.026

5.7 ± 4.0

8/12w (n = 8)

19.9 ± 6.4

13.2 ± 10.2

0.008 ± 0.006

3.4 ± 2.4

a P

< 0.001*

0.009*

< 0.001*

0.104

16/20w (n = 8)

25.8 ± 6.0

16.4 ± 7.1

0.007 ± 0.005

1.7 ± 0.6

a P

< 0.001*

0.029*

< 0.001*

0.007*

b P

0.035#

0.598

0.975

0.218

  1. Note:
  2. 1. FBG: fasting blood glucose; MRglu: myocardial metabolic rate of glucose;Ki: glucose uptake rate constant; SUV: standardized uptake value
  3. 2. aP: P value compared to Control; bP: P value compared to 8/12w group; the differences are significant (P < 0.05) when compared with control group (*) and 8/12w group (#)