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Table 1 Basic characteristics of the included studies (n = 17)

From: Metabolic health and adiposity transitions and risks of type 2 diabetes and cardiovascular diseases: a systematic review and meta-analysis

Study ID

Country

Sample size

Mean age

Male %

Median FU year

Outcome assessed

Metabolic health components

Blood pressure

Plasma glucose

HDL-C

Triacygly-cerols

WC

Feng 2020

China

49,702

66 *

43.7

4.0

T2DM

X

X

X

X

 

Heianza 2014

Japan

27,478

47.3

64.5

6.0

T2DM

X

X

X

X

 

Lee 2015

South Korea

2692

61.7

61.6

8.0

T2DM

X

X

X

X

X

Min 2021

China

4604

54.0

33.8

3.0

T2DM

X

X

X

X

X

Navarro-González 2016

Europe

4340

54.6

50.3

9.0 (male)

9.2 (female)

T2DM

X

X

X

X

 

Song 2022

China

14,894

57.5

39.6

10.1

T2DM

X

X

X

X

X

Wang 2018

China

11,865

49.9

38.0

6.0

T2DM

X

X

X

X

 

Cho 2019

South Korea

362,863

58.9

53.7

2.0

Composite CVD events: admissions for MI and stroke

X

X

X

X

 

Eckel 2018

US

90,257

46.3

0

24.0

Composite CVD events: MI, stroke

X

X

X

  

Gao 2020

China

458,246

50.9

40.8

10.0

Composite CVD events: vascular death, MI, stroke

X

X

 

X

X

Guo 2021

China

7472

53.5

46.6

4.7

Composite CVD events: CHD, stroke

X

X

X

X

X

Hosseinpanah 2020

Iran

6758

42.8

41.6

15.9

Composite CVD events: CHD, stroke, CVD death

X

X

X

X

X

Lee 2022

South Korea

6665

51.7

47.3

17.4

Composite CVD events: MI, congestive heart failure, CAD, cerebrovascular disease, peripheral artery disease

X

X

 

X

 

Lee 2020

South Korea

7,148,763

48.7

56.5

3.7

Composite CVD events: hospitalization for heart failure

X

X

X

X

X

Lin 2020

China

6220

53.9

37.1

4.4

Composite CVD events: MI, stroke, hospitalization or treatment of heart failure

X

X

X

X

 

Mongraw-Chaffin 2018

US

5005

61.1

51.8

12.2

Composite CVD events: CHD, stroke, heart failure

X

X

X

X

 

Mørkedal 2014

Norway

61,299

48.8

46.1

12.2

Composite CVD events: MI

X

X

X

X

 
  1. FU: follow-up; HDL-C: high-density lipoprotein cholesterol; WC: waist circumference; T2DM: type 2 diabetes mellitus; CVD: cardiovascular disease; MI: myocardial infarction; CHD: coronary heart disease; CAD: coronary artery disease; *median age