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Table 3 Baseline characteristics of patients with hyperglycaemic crisis in the training set by clinical outcomes

From: Mortality prediction in patients with hyperglycaemic crisis using explainable machine learning: a prospective, multicentre study based on tertiary hospitals

Variables

Survival group

(n = 226)

Nonsurvival group

(n = 31)

 

Demographic data

   

Age, years

54.5 (37.0, 67.3)

79.5 (65.0, 86.3)

 < 0.001

Sex, %

  

0.194

 Male

137 (60.6)

15 (48.4)

 

 Female

89 (39.4)

16 (51.6)

 

Body mass index, kg/m2

22.8 (20.2, 25.0)

17.5 (20.7, 25.0)

0.076

Diabetes type, %

  

0.015

 Type 1

37 (16.4)

0 (0.0)

 

 Type 2

189 (83.6)

31 (100.0)

 

Clinical and laboratory data

Blood glucose, mmol/L

30.1 (20.2, 33.3)

33.3 (33.3, 38.4)

 < 0.001

β-hydroxybutyrate, mmol/L

4.13 (1.51, 6.20)

3.05 (0.48, 4.60)

0.045

Hemoglobin A1c, %

11.8 (10.2, 13.6)

10.6 (8.6, 12.5)

0.038

Triglyceride, mmol/L

1.89 (1.31, 3.11)

2.10 (1.40, 2.71)

0.386

Total cholesterol, mmol/L

4.80 (3.78, 6.26)

4.39 (3.80, 6.30)

0.675

LDL-C, mmol/L

2.52 (1.73, 3.35)

2.86 (2.01, 3.74)

0.159

Serum creatinine, umol/L

75.5 (56.8, 131.3)

165.0 (87.2, 334.8)

 < 0.001

Blood urea nitrogen, mmol/L

7.50 (5.18, 13.31)

19.5 (11.0, 28.2)

 < 0.001

Cystatin C, mg/L

1.10 (0.69, 1.88)

1.88 (1.28, 3.64)

 < 0.001

Creatine kinase, U/L

50.0 (25.0, 85.1)

32.8 (5.8, 139.8)

0.306

Cardiac troponin I, μg/L

58.5 (30.3, 109.0)

44.0 (20.5, 177.8)

0.477

CKMB, U/L

87.0 (55.0, 187.0)

150.0 (76.5, 571.3)

0.008

Alanine aminotransferase, IU/L

0.01 (0.00, 0.03)

0.04 (0.00, 0.10)

0.021

Aspartate aminotransferase, IU/L

18.0 (12.0, 28.0)

19.0 (14.0, 31.0)

0.200

C-reactive protein, mmol/L

7.90 (3.81, 47.45)

19.1 (4.8, 145.0)

0.048

Procalcitonin, ng/ml

0.40 (0.05, 2.14)

0.71 (0.11, 6.80)

0.063

White blood cells, × 109/L

10.5 (6.7, 14.6)

12.7 (7.1, 17.8)

0.271

Percentage of neutrophils, %

83.7 (73.9, 89.7)

84.1 (76.7, 93.4)

0.136

Lymphocyte, × 109/L

1.08 (0.63, 1.60)

1.00 (0.54, 1.50)

0.513

Platelet, × 109/L

202.0 (153.0, 261.5)

179.0 (133.5, 207.3)

0.085

Serum sodium, mmol/L

140.3 (134.7, 148.2)

149.0 (142.5, 159.4)

0.001

Serum potassium, mmol/L

4.03 (3.68, 4.66)

4.02 (3.62, 4.75)

0.759

Serum chloride, mmol/L

99.9 (95.6, 105.5)

102.5 (96.8, 111.7)

0.220

PH

7.30 (7.22, 7.37)

7.38 (7.25, 7.41)

0.030

Base excess, mmol/L

− 7.50 (− 2.70, − 16.43)

− 7.00 (− 2.50, − 12.00)

0.682

HCO3−, mmol/L

14.6 (7.8, 18.0)

17.6 (13.8, 21.2)

0.031

Effective serum osmolality, mOsm/kg

310.2 (292.0, 330.3)

327.0 (322.0, 353.0)

 < 0.001

Medical history

   

Infection, n (%)

122 (54.0)

25 (80.6)

0.005

Septic shock, n (%)

5 (2.2)

2 (6.5)

0.174

Hypertension, n (%)

57 (25.2)

9 (29.0)

0.649

Coronary heart disease, n (%)

24 (10.6)

5 (16.1)

0.363

Heart failure, n (%)

10 (4.4)

2 (6.5)

0.616

Cerebral infarction, n (%)

32 (14.2)

12 (38.7)

0.001

Dementia, n (%)

3 (1.3)

2 (6.5)

0.053

Diabetic nephropathy, n (%)

34 (15.0)

9 (29.0)

0.050

Acute kidney injury, n (%)

6 (2.7)

2 (6.5)

0.254

Tumor, n (%)

3 (1.3)

0 (0.0)

0.519

  1. LDL-C low-density lipoprotein cholesterol, CKMB creatinine kinases MB isoenzyme, PH hydrogen ion concentration index, HCO3− serum bicarbonate ion concentration. P value < 0.05 was considered statistically significant