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Table 4 Threshold effect analysis of S100A11 on metabolic markers by using two-piecewise linear regression, stratified by gender

From: Association between serum S100A11 levels and glucose metabolism in diabetic process

 

Inflection points of HbA1c

Inflection points of DIO (the liver)

Inflection points of CIR

β

(95%CI)

P

β

(95%CI)

P

β

(95%CI)

P

Male

 > 11.24

0.16 (0.03, 0.29)

0.0245

 > 5.49

200.77 (9.58, 391.96)

0.0478

 > 7.44

23.70 (− 1.02, 48.42)

0.0699

 ≤ 11.24

 − 0.51 (− 0.98, − 0.05)

0.0388

 ≤ 5.49

 − 47.30 (− 143.29, 48.69)

0.3414

 ≤ 7.44

 − 11.20 (− 37.60, 15.20)

0.4122

Female

 > 5.28

0.23 (− 0.04, 0.50)

0.1076

 > 3.04

676.51 (− 65.08, 1418.11)

0.0802

 > 2.85

113.93 (24.32, 203.54)

0.0165

 ≤ 5.28

 − 0.13 (− 0.36, 0.09)

0.2393

 ≤ 3.04

 − 51.17 (− 204.06, 101.73)

0.5151

 ≤ 2.85

 − 14.30 (− 30.96, 2.35)

0.0992

  1. Effect: HbA1c, DIo (the liver), CIR; cause: S100A11
  2. Adjusted: glucose tolerance, age, BMI, WHR, 0.5hPPG/0.5hPPI/HbA1c/FPG/FPI