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Table 5 Relationship between the levels of T-VDR expression and the clinical features of DFO patients [( ± s), n (%)]

From: Level of 25-hydroxyvitamin D and vitamin D receptor in diabetic foot ulcer and factor associated with diabetic foot ulcers

 

High expression group

(n = 32)

Low expression group

(n = 52)

P value

Age (y)

55.6 ± 10.5

56.4 ± 11.1

0.482

Sex

  

0.830

 Male

18 (56.3)

28 (53.8)

 

 Female

14 (43.7)

24 (46.2)

 

Ulcer area (cm2)

  

0.786

 ≤ 5

3 (9.4)

7 (13.5)

 

 5 ~ 10

18 (56.3)

30 (57.7)

 

 > 10

11 (34.3)

15 (28.8)

 

Ulcer duration (week)

  

0.037

 ≤ 6

4 (12.5)

5 (9.6)

 

 6 ~ 10

18 (56.3)

16 (30.8)

 

 > 10

10 (31.2)

31 (59.6)

 

Wagner grade

  

0.011

 II

0 (0.0)

0 (0.0)

 

 III

25 (75.0)

25 (46.1)

 

 IV

7 (18.7)

27 (48.1)

 

Severity of infection

  

0.041

 Mild

0 (0.0)

0 (0.0)

 

 Moderate

24 (75.0)

27 (51.9)

 

 Severe

8 (25.0)

25 (48.1)

 

Recurrent DFU

8 (25.0)

26 (50.0)

0.023

Detection rate of drug resistant bacteria

7 (21.9)

27 (51.9)

0.006

Outcome of ulcer after 8 weeks

  

0.021

 Healing

20 (62.5)

19 (36.5)

 

 Non-healing

12 (37.5)

33 (63.5)

 

Amputation rate (%)

  

0.039

 Amputation

5 (15.6)

19 (36.5)

 

 Non-amputation

27 (84.4)

33 (63.5)

 
  1. Data are presented mean ± standard deviations or numbers (%); Differences between two groups analyzed using t test or x2 test. The cut-off point of vitamin D receptor expression level for grouping was 2.68
  2. DFU diabetic foot ulcer, DFO diabetic foot osteomyelitis