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Table 4 Relationship between the levels of T-VDR expression and the clinical features of DFU patients [( ± s), n (%)]

From: Level of 25-hydroxyvitamin D and vitamin D receptor in diabetic foot ulcer and factor associated with diabetic foot ulcers

 

High expression group

(n = 53)

Low expression group

(n = 103)

P value

Age (y)

55.1 ± 10.8

55.8 ± 11.3

0.613

Sex

  

0.162

 Male

34 (64.2)

54 (52.4)

 

 Female

19 (35.8)

49 (47.6)

 

Ulcer area (cm2)

  

0.787

 ≤ 5

7 (13.2)

17 (16.5)

 

 5 ~ 10

30 (56.6)

57 (55.4)

 

 > 10

16 (30.2)

29 (28.1)

 

Ulcer duration (week)

  

0.014

 ≤ 6

9 (17.0)

12 (11.7)

 

 6 ~ 10

32 (60.4)

43 (41.7)

 

 > 10

12 (22.6)

48 (46.6)

 

Wagner grade

  

0.030

 II

12 (22.6)

8 (7.7)

 

 III

32 (60.3)

76 (73.9)

 

 IV

9 (7.1)

19 (18.4)

 

Severity of infection

  

0.021

 Mild

12 (22.6)

8 (7.8)

 

 Moderate

26 (49.1)

68 (66.0)

 

 Severe

15 (28.3)

27 (26.2)

 

Recurrent DFU

11 (20.8)

40 (38.8)

0.023

Detection rate of drug resistant bacteria

10 (18.9)

41 (39.8)

0.012

Outcome of ulcer after 8 weeks

  

0.016

 Healing

35 (66.0)

47 (45.6)

 

 Non-healing

18 (34.0)

56 (54.4)

 

Amputation rate (%)

  

0.040

 Amputation

8 (15.1)

31 (30.1)

 

 Non-amputation

45 (84.9)

72 (69.9)

 
  1. Data are presented mean ± standard deviations or numbers (%); Differences between two groups analyzed using t test or x2 test. The cut-off point of vitamin D receptor expression level for grouping was 2.68
  2. DFU diabetic foot ulcer