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Table 3 Relationship between serum 25(OH)VD levels and the clinical features of DFU patients [( ± s), n (%)]

From: Level of 25-hydroxyvitamin D and vitamin D receptor in diabetic foot ulcer and factor associated with diabetic foot ulcers

 

High level group

(n = 58)

Low level group

(n = 98)

P value

Age (y)

54.8 ± 10.8

56.2 ± 11.3

0.426

Sex

  

0.273

 Male

36 (62.1)

52 (53.1)

 

 Female

22 (37.9)

46 (46.9)

 

Ulcer area (cm2)

  

0.856

 ≤ 5

8 (13.8)

16 (16.3)

 

 5 ~ 10

32 (55.2)

55 (56.1)

 

 > 10

18 (31.0)

27 (27.6)

 

Ulcer duration (week)

  

0.043

 ≤ 6

10 (17.2)

11 (11.2)

 

 6 ~ 10

33 (56.9)

42 (42.9)

 

 > 10

15 (25.9)

45 (45.9)

 

Wagner grade

  

0.005

 II

14 (24.1)

6 (6.1)

 

 III

35 (60.3)

73 (74.5)

 

 IV

9 (15.6)

19 (19.4)

 

Severity of infection

  

0.003

 Mild

14 (24.1)

6 (6.1)

 

 Moderate

28 (48.3)

66 (67.3)

 

 Severe

16 (27.6)

26 (26.6)

 

Recurrent DFU

12 (20.7)

39 (39.8)

0.014

Detection rate of drug resistant bacteria

13 (22.4)

38 (38.8)

0.035

Outcome of ulcer after 8 weeks

  

0.031

 Healing

37 (63.8)

45 (45.9)

 

 Non-healing

21 (36.2)

53 (54.1)

 

Amputation rate (%)

  

0.035

 Amputation

9 (15.5)

30 (30.6)

 

 Non-amputation

49 (84.5)

68 (69.4)

 
  1. Data are presented mean ± standard deviations or numbers (%); Differences between two groups analyzed using t test or x2 test. The cut-off point of serum vitamin D level for grouping was 10.3 ng/mL
  2. DFU diabetic foot ulcer, 25(OH)VD 25-hydroxyvitamin D