Table 2 Changes of all the laboratory results
Pre (0w) | Post treatment (12w) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Control | SGLT2i | CRIC | Control | %â–³Control | SGLT2i | %â–³SGLT2i | CRIC | %â–³CRIC | |
HbA1c (%) | 12.9 ± 1.8 | 11.8 ± 1.3 | 12.8 ± 1.8 | 5.6 ± 0.6 | − 55.5 ± 8.7 | 6.1 ± 0.6 | − 48.4 ± 7.7 | 6.1 ± 0.7 | − 51.9 ± 7.0 |
T-CHO (mg/dl) | 196.4 ± 36.2 | 192.1 ± 43.7 | 239.9 ± 29.8**,*** | 164.5 ± 32.8 | − 15.5 ± 13.7 | 199.9 ± 60.5 | − 2.0 ± 14.0* | 205.0 ± 28.9** | − 14.1 ± 10.8 |
HDL-C (mg/dl) | 44.6 ± 9.1 | 49.9 ± 13.0 | 50.9 ± 10.8 | 47.5 ± 8.1 | 7.5 ± 10.7 | 59.4 ± 17.2 | 18.1 ± 12.7 | 59.6 ± 10.1** | 18.5 ± 15.9 |
LDL-C (mg/dl) | 119.4 ± 28.6 | 119.3 ± 38.3 | 163.6 ± 29.2**,*** | 102.4 ± 30.9 | − 14.9 ± 19.2 | 125.4 ± 52.2 | − 3.1 ± 14.6 | 132.7 ± 32.6** | − 18.9 ± 13.8*** |
TG (mg/dl) | 146.3 ± 56.3 | 166.9 ± 94.8 | 170.9 ± 119.7 | 92.4 ± 44.4 | − 35.5 ± 25.0 | 107.0 ± 44.6 | − 25.0 ± 25.2 | 85.6 ± 17.4 | − 37.8 ± 22.4 |
Leptin (ng/ml) | 19.4 ± 11.7 | 12.3 ± 6.7 | 13.3 ± 6.4 | 21.3 ± 19.5 | 11.9 ± 57.0 | 13.5 ± 8.1 | 17.6 ± 36.9 | 22.1 ± 19.0 | 55.2 ± 87.7 |
H-M adiponectin (µg/ml) | 1.76 ± 0.80 | 1.81 ± 1.55 | 1.86 ± 0.66 | 2.47 ± 1.04 | 53.7 ± 62.5 | 3.18 ± 2.34 | 71.5 ± 44.4 | 2.85 ± 1.66 | 50.8 ± 59.3 |
T-ketone (µmol/l) | 557.6 ± 753.1 | 329.2 ± 314.4 | 751.7 ± 1172.0 | 256.8 ± 245.4 | − 5.7 ± 87.3 | 349.0 ± 496.4 | − 25.8 ± 71.3 | 173.0 ± 121.5 | − 24.8 ± 91.7 |
AcAc (µmol/l) | 124.1 ± 116.4 | 96.8 ± 76.8 | 205.1 ± 298.7 | 77.8 ± 66.8 | 4.1 ± 100.6 | 75.4 ± 76.4 | − 28.0 ± 58.5 | 52.1 ± 40.6 | − 29.8 ± 89.3 |
3-OHBA (µmol/l) | 433.4 ± 638.4 | 232.3 ± 238.5 | 546.6 ± 873.5 | 179.0 ± 179.6 | − 8.3 ± 84.1 | 273.6 ± 425.7 | − 24.6 ± 78.0 | 120.9 ± 82.6 | − 22.2 ± 93.2 |