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Table 1 Characteristics and anthropometric measurements of the study subjects

From: SGLT2 inhibitor versus carbohydrate-restricted isocaloric diet: reprogramming substrate oxidation in type 2 diabetes

 

Pre (0w)

Post treatment (12w)

Control

SGLT2i

CRIC

Control

%â–³Control

SGLT2i

%â–³SGLT2i

CRIC

%â–³CRIC

Duration of diabetes (years)

0.8 ± 0.6

4.4 ± 2.6

4.5 ± 2.1

–

–

–

–

–

–

Age (years)

50.4 ± 14.0

53.8 ± 15.2

56.9 ± 15.6

–

–

–

–

–

–

Sex (Male/Female)

4/4

6/2

4/3

–

–

–

–

–

–

Height (cm)

165.5 ± 12.4

165.2 ± 9.5

160.9 ± 7.8

–

–

–

–

–

–

Weight (kg)

75.9 ± 16.6

72.7 ± 18.7

65.4 ± 9.4

71.7 ± 15.8

-2.2 ± 6.8

70.2 ± 16.5

1.1 ± 5.0

66.8 ± 9.8

2.4 ± 6.2

BMI (kg/m2)

27.7 ± 5.1

26.3 ± 5.1

25.2 ± 3.0

26.2 ± 4.1

-2.2 ± 6.8

25.9 ± 4.4

1.1 ± 5.0

25.8 ± 2.8

2.4 ± 6.2

Total body muscle mass (kg)

49.2 ± 12.3

51.1 ± 13.1

42.8 ± 6.4

50.5 ± 15.6

2.7 ± 6.2

50.3 ± 12.7

3.0 ± 2.0

46.6 ± 8.1

8.6 ± 5.8 * **

Total body fat mass (kg)

23.5 ± 12.0

18.4 ± 6.5

19.9 ± 5.5

17.9 ± 10.1

-15.5 ± 25.2

16.8 ± 4.7

-2.1 ± 20.3

17.3 ± 6.3

-12.6 ± 16.7

  1. Data are mean ± standard deviation
  2. %â–³Control, %â–³SGLT2i, %â–³CRIC: percentage differs from 12 to 0w in various parameters
  3. SGLT2i, renal sodium/glucose cotransporter-2 inhibitor; CRIC, carbohydrate restricted iso-caloric diet
  4. *p < 0.05 (t test) %△Control vs %△CRIC
  5. **p < 0.05 (t test) %△SGLT2i vs %△CRIC