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Table 5 HRs (95% CI) of quartiles of TG/HDL-C for incident prediabetes† and T2DM†† among women

From: Association of triglycerides to high-density lipoprotein cholesterol ratio to identify future prediabetes and type 2 diabetes mellitus: over one-decade follow-up in the Iranian population

 

Quartiles of TG/HDL-C

P

for trend

First

Second

Third

Fourth

Normoglycemia††† to incident prediabetes

 

TG/HDL-C < 0.77

0.77 ≤ TG/HDL-C < 1.19

1.19 ≤ TG/HDL-C < 1.84

TG/HDL-C ≥ 1.84

 
 

(E/N = 179/705)

(E/N = 239/704)

(E/N = 283/704)

(E/N = 369/704)

 

Model 1

Reference

1.40 (1.15–1.70)

1.69 (1.40–2.04)

2.53 (2.12–3.03)

 < 0.001

Model 2

Reference

1.14 (0.94–1.39)

1.20 (0.99–1.46)

1.57 (1.29–1.91)

 < 0.001

Model 3

Reference

1.06 (0.87–1.29)

1.13 (0.93–1.37)

1.45 (1.19–1.76)

 < 0.001

Normoglycemia to incident T2DM

 

TG/HDL-C < 0.77

0.77 ≤ TG/HDL-C < 1.19

1.19 ≤ TG/HDL-C < 1.84

TG/HDL-C ≥ 1.84

 
 

(E/N = 22/705)

(E/N = 30/704)

(E/N = 58/704)

(E/N = 92/704)

 

Model 1

Reference

1.36 (0.78–2.35)

2.65 (1.62–4.33)

4.52 (2.84–7.19)

 < 0.001

Model 2

Reference

1.03 (0.59–1.80)

1.79 (1.08–2.96)

2.55 (1.55–4.18)

 < 0.001

Model 3

Reference

0.94 (0.54–1.65)

1.67 (1.00–2.77)

2.36 (1.44–3.87)

 < 0.001

Prediabetes to incident T2DM

 

TG/HDL-C < 1.23

1.23 ≤ TG/HDL-C < 1.80

1.80 ≤ TG/HDL-C < 2.81

TG/HDL-C ≥ 2.81

 
 

(E/N = 60/192)

(E/N = 71/192)

(E/N = 92/192)

(E/N = 99/191)

 

Model 1

Reference

1.28 (0.91–1.80)

1.69 (1.22–2.35)

2.00 (1.45–2.76)

 < 0.001

Model 2

Reference

1.23 (0.87–1.73)

1.59 (1.14–2.21)

1.86 (1.34–2.58)

 < 0.001

Model 3

Reference

1.30 (0.92–1.85)

1.62 (1.16–2.47)

1.84 (1.32–2.55)

 < 0.001

  1. Model 1: unadjusted model; Model 2: adjusted for age, body mass index, waist-to-height ratio, wrist circumference, systolic blood pressures, family history of diabetes, education level, history of cardiovascular disease; Model 3: Model 2 + fasting plasma glucose
  2. HR hazard ratio, CI confidence interval, TG/HDL-C triglycerides to high density lipoprotein cholesterol ratio, T2DM type 2 diabetes mellitus, E number of events, N number of population, FPG fasting plasma glucose, 2 h-PCG 2-h post-challenge plasma glucose
  3. † Predibetes: 5.6 mmol/L ≤ FPG < 7.0 mmol/L or 7.8 mmol/L ≤ 2 h-PCG < 11.1 mmol/L)
  4. †† T2DM: FPG ≥ 7.0 mmol/L or 2 h-PCG ≥ 11.1 mmol/L or using antidiabetic medications
  5. ††† Normoglycemia includes NFG and NGT