| Total | IC score 0 | IC score 1 | IC score ≥ 2 | p-value |
---|---|---|---|---|---|
Number | 2482 | 1525 | 655 | 302 | Â |
Age (years) | 72.4 ± 5.8 | 71.2 ± 5.0 | 73.2 ± 5.9 | 77.0 ± 6.6 |  < 0.0001 |
Sex, female (n, %) | 1374(55.4) | 790(51.8) | 393(60.0) | 191(63.3) |  < 0.0001 |
Diabetes duration (years) | 13.5 ± 9.0 | 13.1 ± 8.8 | 13.7 ± 9.2 | 15.2 ± 9.2 | 0.001 |
Hypertension (n, %) | 1552(62.5) | 917(60.1) | 438(66.9) | 197(65.2) | 0.007 |
Hyperlipidemia (n, %) | 1956(78.8) | 1217(79.8) | 503(76.8) | 236(78.2) | 0.276 |
Current smoker (n, %) | 486(19.6) | 315(20.7) | 121(18.5) | 50(16.6) | 0.184 |
Body mass index (kg/m2) | 25.6 ± 4.0 | 25.4 ± 3.8 | 26.0 ± 4.2 | 25.8 ± 4.2 | 0.001 |
Waist-to-hip ratio | 0.93 ± 0.07 | 0.92 ± 0.07 | 0.93 ± 0.07 | 0.93 ± 0.07 | 0.156 |
SBP (mmHg) | 129 ± 16 | 128 ± 15 | 130 ± 16 | 130 ± 19 | 0.076 |
DBP (mmHg) | 73 ± 11 | 73 ± 11 | 73 ± 11 | 73 ± 11 | 0.669 |
Obesity status (n, %) | |||||
 Underweight | 35(1.4) | 19(1.3) | 11(1.7) | 5(1.7) | 0.681 |
 Normal weight | 886(35.7) | 571(37.4) | 210(32.1) | 105(34.8) | 0.052 |
 Overweight | 782(31.5) | 485(31.8) | 199(30.4) | 98(32.5) | 0.752 |
 Mild obesity | 451(18.2) | 278(18.2) | 129(19.7) | 44(14.6) | 0.160 |
 Moderate obesity | 274(11.0) | 147(9.6) | 88(13.4) | 39(12.9) | 0.019 |
 Severe obesity | 54(2.2) | 25(1.6) | 18(2.8) | 11(3.6) | 0.047 |
KDIGO CKD risk stage (n, %) | |||||
 Low risk | 1167(47.0) | 789(51.7) | 289(44.1) | 89(29.5) |  < 0.0001 |
 Moderately increased risk | 610(24.6) | 379(24.9) | 154(23.5) | 77(25.5) | 0.740 |
 High risk | 368(14.8) | 192(12.6) | 108(16.5) | 68(22.5) |  < 0.0001 |
 Very high risk | 337(13.6) | 165(10.8) | 104(15.9) | 68(22.5) |  < 0.0001 |
Type of treatment (%) | |||||
 (OHA/Insulin/Both) | 67.8/3.2/29.1 | 71.6/2.1/26.3 | 65.5/4.6/30.0 | 53.7/5.3/41.0 |  < 0.0001 |
 Statins (n, %) | 1919(77.3) | 1193(78.2) | 494(75.4) | 232(76.8) | 0.348 |
 ARB (n, %) | 1085(43.7) | 626(41.1) | 317(48.4) | 142(47.0) | 0.003 |
Biochemical characteristics | |||||
 HbA1c (%) | 7.3 ± 1.2 | 7.2 ± 1.1 | 7.2 ± 1.2 | 7.5 ± 1.4 | 0.006 |
 Fasting glucose (mmol/L) | 8.5 ± 3.4 | 8.4 ± 3.3 | 8.5 ± 3.4 | 8.9 ± 3.8 | 0.001 |
 Total cholesterol (mmol/L) | 4.1 ± 0.8 | 4.1 ± 0.8 | 4.1 ± 0.8 | 4.0 ± 0.8 | 0.671 |
 Triglycerides (mmol/L) | 1.3 ± 0.7 | 1.3 ± 0.8 | 1.3 ± 0.7 | 1.3 ± 0.6 | 0.694 |
 HDL cholesterol (mmol/L) | 1.4 ± 0.4 | 1.4 ± 0.4 | 1.4 ± 0.4 | 1.4 ± 0.4 | 0.986 |
 LDL cholesterol (mmol/L) | 2.1 ± 0.6 | 2.1 ± 0.6 | 2.1 ± 0.7 | 2.1 ± 0.6 | 0.503 |
 Uric acid (mmol/L) | 5.4 ± 1.6 | 0.3 ± 0.1 | 0.3 ± 0.1 | 0.3 ± 0.1 | 0.841 |
 eGFR (ml/min/1.73m2) | 68.9 ± 22.0 | 77.2 ± 20.5 | 73.3 ± 21.5 | 71.0 ± 23.0 |  < 0.0001 |
 UACR (mg/g) | 19.2(9.7–54.3) | 17.1(8.8–46.5) | 21.0(10.9–60.9) | 29.3(13.4–83.6) |  < 0.0001 |
 Creatinine (µmol/L) | 97.2 ± 53.0 | 94.6 ± 48.6 | 102.5 ± 67.2 | 107.9 ± 56.6 |  < 0.0001 |
 Hemoglobin (g/L) | 136 ± 17 | 138 ± 17 | 133 ± 17 | 131 ± 17 |  < 0.0001 |