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Fig. 5 | Diabetology & Metabolic Syndrome

Fig. 5

From: Maternal hyperglycemia inhibits pulmonary vasculogenesis during mouse fetal lung development by promoting GβL Ubiquitination-dependent mammalian target of Rapamycin assembly

Fig. 5

The TRAF2 knockdown restored the MFLEC angiogenesis impaired by the high glucose. A Expression level of TRAF2 protein. B Expression level of TRAF2 mRNA. C The association between GβL and mTOR, Raptor, Rictor, Sin1, and ubiquitin was evaluated using the immunoprecipitation assay. D The cell angiogenesis ability under high-glucose conditions (HG: high glucose, n = 3 in triplicate, ***p < 0.001)

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