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Table 2 Cox proportional hazards regression analysis for long-term all-cause mortality

From: Prognostic value of creatinine-to-cystatin c ratio in patients with type 2 diabetes mellitus: a cohort study

 

Univariable

Multivariable

HR (95%CI)

p-value

aHR (95%CI)

p-value

Scr/Scys

 Per 0.1-point decrement (continuous)

1.05 (1.01–1.10)

0.020

1.08 (1.03–1.13)

0.009

 Low-MM (Men < 1.0, Women < 0.8)

1.30 (1.04–1.64)

0.022

1.36 (1.03–1.75)

0.021

 Age ≥ 60 years

1.52 (1.21–1.91)

 < 0.001

1.34 (1.04–1.74)

0.024

 Female

0.88 (0.70–1.11)

0.271

0.78 (0.60–1.01)

0.063

 BMI

1.02 (0.98–1.06)

0.077

1.01 (0.98–1.03)

0.069

 Smoking

1.18 (1.12–1.24)

0.029

1.12 (1.03–1.20)

0.048

 Hypertension

1.11 (0.89–1.37)

0.355

1.12 (0.88–1.43)

0.351

 CHF

1.85 (1.35–2.55)

 < 0.001

1.64 (1.14–2.36)

0.008

 CAD

0.80 (0.63–1.02)

0.070

0.95 (0.75–1.15)

0.091

 Stroke

1.98 (1.39–2.81)

 < 0.001

1.86 (1.13–2.59)

0.017

 COPD

1.94 (0.73–5.21)

0.187

1.95 (0.72–5.27)

0.186

 Anemia

1.29 (1.03–1.61)

0.024

1.24 (0.96–1.59)

0.097

 HbA1c

1.08 (1.01–1.16)

0.034

1.09 (1.02–1.18)

0.022

 TG

0.92 (0.84–1.01)

0.095

1.03 (0.92–1.14)

0.079

 HDL-C

0.99 (0.65–1.52)

0.971

1.20 (0.79–1.61)

0.381

 LDL-C

0.99 (0.89–1.11)

0.925

1.07 (0.95–1.21)

0.267

  1. BMI body mass index, CHF congestive heart failure, CAD coronary artery disease; COPD chronic obstructive pulmonary disease, HbA1c glycosylated hemoglobin, TG triglyceride, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol