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Table 1 Baseline characteristics of patients in normal-MM and low-MM groups

From: Prognostic value of creatinine-to-cystatin c ratio in patients with type 2 diabetes mellitus: a cohort study

Characteristic

Normal-MM (n = 1477)

Low-MM (n = 2191)

p-value

Demographic characteristics

 Age (years)

60.3 ± 9.7

63.8 ± 9.8

 < 0.001

 Age ≥ 60 years, n (%)

790 (53.5)

1471 (67.1)

 < 0.001

 Female, n (%)

489 (33.1)

696 (31.8)

0.415

 BMI(kg/m2)

23.5 ± 3.0

24.0 ± 3.5

0.072

 Smoking, n (%)

529 (35.8)

857 (39.1)

0.043

 Alcohol drinking, n (%)

601 (40.7)

914 (42.7)

0.232

Medical history and clinical condition

 Hypertension, n (%)

877 (59.4)

1329 (60.7)

0.458

 CHF, n (%)

129 (8.7)

197 (9.0)

0.834

 CAD, n (%)

1178 (79.8)

1705 (77.8)

0.173

 Stroke, n (%)

85 (5.8)

125 (5.7)

1.000

 COPD, n (%)

3 (0.2)

19 (0.9)

0.019

 Anemia, n (%)

375 (25.4)

651 (29.7)

0.005

Laboratory examination

 Scr/Scys

1.13 ± 0.27

0.77 ± 0.14

 < 0.001

 Scr(mg/dl)

0.93 ± 0.18

0.85 ± 0.19

 < 0.001

 Cystatin C(mg/L)

0.84 ± 0.17

1.13 ± 0.26

 < 0.001

 eGFR(ml/min/1.73m2)

83.59 ± 16.68

92.72 ± 22.89

 < 0.001

 FBG(mmol/L)

8.99 ± 4.18

9.74 ± 4.61

 < 0.001

 2hPBG(mmol/L)

11.83 ± 4.43

12.51 ± 4.65

0.009

 HbA1C (%)

7.58 ± 1.57

7.69 ± 1.64

0.089

 TG(mmol/L)

1.51 (1.10, 2.16)

1.44 (1.07, 2.04)

0.004

 TC(mmol/L)

4.57 ± 1.26

4.49 ± 1.17

0.070

 HDL-C(mmol/L)

0.98 ± 0.25

0.96 ± 0.24

0.011

 LDL-C(mmol/L)

2.81 ± 0.95

2.75 ± 0.94

0.047

Medications at discharge

 OADs, n (%)

773 (53.0)

1137 (52.5)

0.788

 Statins, n (%)

1313 (90.0)

1918 (88.5)

0.176

 Aspirin, n (%)

1222 (83.8)

1751 (80.8)

0.026

 ACEI/ARB, n (%)

618 (42.4)

975 (45.0)

0.125

 CCB, n (%)

279 (19.1)

475 (21.9)

0.046

  1. BMI body mass index, CHF congestive heart failure, CAD coronary artery disease, COPD chronic obstructive pulmonary disease, Scr/Scys serum creatinine-to-cystatin C ratio, Scr serum creatinine, eGFR estimated glomerular filtrationrate, FBG Fasting blood glucose, 2 h PBG 2 h postprandial blood glucose, HbA1c glycosylated hemoglobin, TG triglyceride, TC total cholesterol, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, OADs oral antidiabetic drugs, ACEI/ARB angiotensin-converting enzyme inhibitor/angiotensin receptor blocker, CCB calcium channel blocker