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Table 1 Basic characteristics of the study subjects

From: Gender differences in the association between insulin resistance and chronic kidney disease in a Chinese population with metabolic syndrome

Variables

Total

Men

Women

p value

(n = 5061)

(n = 3253)

(n = 1808)

Age (year)

50

[43, 58]

47

[41, 54]

56

[50, 61]

 < 0.001

Waist circumference (cm)

92

[87, 96]

94

[90, 98]

87

[82, 91]

 < 0.001

Waist-to-height ratio

0.55

[0.53, 0.58]

0.55

[0.53, 0.58]

0.55

[0.53, 0.59]

0.13

BMI (kg/m2)

26.44

[24.72, 28.26]

26.82

[25.27, 28.53]

25.58

[23.84, 27.54]

 < 0.001

SBP (mmHg)

133

[121, 144]

132

[121, 141]

135

[121, 148]

 < 0.001

DBP (mmHg)

81

[73, 88]

84

[75, 90]

77

[70, 85]

 < 0.001

MAP (mmHg)

99

[90, 106]

99.67

[91.67, 106.67]

96.67

[88.00, 104.92]

 < 0.001

FBG (mmol/L)

5.67

[5.19, 6.32]

5.69

[5.18, 6.37]

5.65

[5.21, 6.23]

0.17

Total cholesterol (mmol/L)

5.32

[4.67, 6.01]

5.31

[4.67, 5.98]

5.34

[4.68, 6.05]

0.25

TG (mmol/L)

2.05

[1.52, 2.82]

2.23

[1.76, 3.10]

1.76

[1.21, 2.31]

 < 0.001

LDL-C (mmol/L)

3.33

[2.75, 3.95]

3.31

[2.72, 3.95]

3.36

[2.79, 3.97]

0.22

HDL-C (mmol/L)

1.04

[0.93, 1.20]

0.99

[0.9, 1.12]

1.16

[1.04, 1.27]

 < 0.001

Insulin (μIU/L)

8.3

[6.2, 11.2]

8.4

[6.2, 11.4]

8.0

[6.1, 10.8]

0.01

HOMA-IR

2.16

[1.57, 3.04]

2.20

[1.59, 3.11]

2.09

[1.53, 2.92]

0.001

eGFR (ml/min/1.73 m2)

98.21

[88.56, 106.17]

98.58

[88.04, 106.89]

97.75

[89.47, 104.41]

0.03

ACR (mg/g)

6.31

[3.73, 13.69]

5.38

[3.27, 11.41]

8.07

[5.01, 17.10]

 < 0.001

Albuminuria, n (%)

612

(12.09%)

337

(10.36%)

275

(15.21%)

 < 0.001

ACR, n (%)

      

 < 0.001

 normoalbuminuria (ACR < 30)

4449

(87.91%)

2916

(89.64%)

1533

(84.79%)

 

 microalbuminuria (ACR 30–299)

562

(11.10%)

311

(9.56%)

251

(13.88%)

 

 macroalbuminuria (ACR >  = 300)

50

(0.99%)

26

(0.80%)

24

(1.33%)

 

CKD, n (%)

      

 < 0.001

 Normal

4405

(87.04%)

2885

(88.69%)

1520

(84.07%)

 

 Stage 1

395

(7.80%)

202

(6.21%)

193

(10.67%)

 

 Stage 2

192

(3.79%)

117

(3.60%)

75

(4.15%)

 

 Stage 3

69

(1.36%)

49

(1.51%)

20

(1.11%)

 

CKD stage 1 ~ 3, n (%)

656

(12.96%)

368

(11.31%)

288

(15.93%)

 < 0.001

  1. Continuous data are shown as medians [Q1, Q3] and compared using Mann–Whitney U test. Categorical data are shown as n (%) and compared using the Chi-square test
  2. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, MAP mean arterial pressure, FBG fasting blood glucose, TG triglycerides, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, HOMA-IR homeostasis model assessment of insulin resistance, eGFR estimated glomerular filtration rate, ACR albumin/creatinine ratio, CKD chronic kidney disease
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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