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Table 3 Association between HbA1c quartiles and SUA levels

From: Interaction of sex and diabetes on the association between hemoglobin glycation index, hemoglobin A1c and serum uric acid

HGI

Univariate analysis

Multivariate analysisa

β(SE)

P

β(SE)

P

DM Women (N = 682)

Q1

Ref

–

Ref

–

Q2

− 5.3(8.3)

0.52

− 10.3(7.6)

0.18

Q3

− 13.0(8.3)

0.12

− 13.3(7.6)

0.08

Q4

− 42.1(8.2)

 < 0.001*

− 53.0(7.7)

 < 0.001*

P trend

–

 < 0.001*

–

 < 0.001*

Non-DM women (N = 14262)

Q1

Ref

–

Ref

–

Q2

3.1(1.4)

0.03

2.4(1.3)

0.06

Q3

9.2(1.5)

 < 0.001*

5.1(1.4)

 < 0.001*

Q4

30.1(1.4)

 < 0.001*

13.4(1.6)

 < 0.001*

P trend

–

 < 0.001*

–

 < 0.001*

DM men (N = 1681)

Q1

Ref

–

Ref

–

Q2

− 10.0(6.1)

0.10

− 12.4(5.7)

0.03*

Q3

− 22.9(6.1)

 < 0.001*

− 23.3(5.7)

 < 0.001*

Q4

− 52.6(6.2)

 < 0.001*

− 55.1(5.9)

 < 0.001*

P trend

–

 < 0.001*

–

 < 0.001*

Non-DM men (N = 14147)

Q1

Ref

–

Ref

–

Q2

2.3(2.1)

0.27

1.0(1.9)

0.60

Q3

8.2(2.2)

 < 0.001*

5.5(2.1)

0.008*

Q4

7.8(2.1)

 < 0.001*

4.1(2.1)

0.051

P trend

–

 < 0.001*

–

0.01*

  1. HbA1c hemoglobin A1c, SUA serum uric acid, DM diabetes mellitus, SE standard error, Ref reference, others are the same with Table 1
  2. aAdjusted for age, BMI, HGB, TC, LDL-C, TG, BUN, Hcy, hypertension, and dyslipidemia
  3. *P < 0.05
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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