Table 2 Included studies reporting T2D risk in a population with obesity with NGT or prediabetes
Study | Year | Country | Glycemic status | BMI (kg/m2) | Risk | Note |
|---|---|---|---|---|---|---|
Blume et al. [57] | 2015 | USA | NGT | 30.0–34.9 | HR 3.4 | Relative to normal weight (BMI 18.5–25.0) |
35.0–39.9 | HR 5.8 | |||||
≥ 40 | HR 9.5 | |||||
Prediabetes | 30–34.9 | HR 2.0 | ||||
35.0–39.9 | HR 2.5 | |||||
≥ 40 | HR 2.9 | |||||
Ligthart et al. [34] | 2016 | Netherlands | NGT | 30.0–34.9 | AR 43.9% (95% CI 38.6–49.2) | Absolute risk of developing T2D at age 45 years |
≥ 35 | AR 56.6% (95% CI 46.7–66.6) | |||||
Prediabetes | 30.0–34.9 | AR 87.7% (95% CI 79.4–96.0) | ||||
≥ 35 | AR 80.9% (95% CI 65.9–95.9) | |||||
Zatońska et al. [58] | 2020 | Poland | Pooled NGT and prediabetes | ≥ 30 | HR 5.731 (95% CI 2.56–12.82) | Relative to normal weight (BMI 18.5–24.9) |