Effects of fetal famine exposure on the cardiovascular disease risk in the metabolic syndrome individuals

Table 3 Sensitivity analysis

Components	Case/total	IR (per 1000 person-years)	Model 1 HR(95% CI)	Model 2 HR(95% CI)	Model 3 HR(95% CI)
Delete events that occurred within 2 years
No-exposed	180/3107	4.62	1 (Reference)	1 (Reference)	1 (Reference)
Uterine exposed	173/1762	8.01	1.40(1.10,1.78)	1.35(1.06,1.71)	1.31(1.03,1.67)
Childhood exposed	941/8792	8.88	1.13(0.82,1.56)	1.09(0.79,1.50)	1.06(0.77,1.47)
Delete lost-to-review individuals
No-exposed	176/2981	4.71	1 (Reference)	1 (Reference)	1 (Reference)
Uterine exposed	166/1700	7.95	1.39(1.09,1.78)	1.34(1.05,1.72)	1.31(1.03,1.68)
Childhood exposed	878/8300	8.73	1.14(0.82,1.59)	1.10(0.79,1.53)	1.08(0.78,1.50)

Model 1: Adjusted for age, and gender
Model 2: Included covariates in model 1 and further adjusted for education (junior high school or below, senior high school or above), smoking (current, never/former), drinking (current, never/former), and physical activity (current, never/former)
Model 3: Included covariates in model 2 and further adjusted for low-density lipoprotein, hypertension, diabetes, use of antihypertensive medications, use of hypoglycemic medications, and use of hypolipidemic medications

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