Skip to main content

Table 2 Cox proportional hazard model analysis of different famine groups and the incidence of CVD

From: Effects of fetal famine exposure on the cardiovascular disease risk in the metabolic syndrome individuals

Components

Case/total

IR (per 1000 person-years)

Model 1 HR(95%CI)

Model 2 HR(95%CI)

Model 3 HR(95%CI)

CVD

No-exposed

183/3119

4.70

1 (Reference)

1 (Reference)

1 (Reference)

Uterine exposed

180/1777

8.32

1.41(1.11–1.78)

1.35(1.06–1.72)

1.32(1.04–1.67)

Childhood exposed

964/8848

9.09

1.10(0.80–1.51)

1.05(0.76–1.45)

1.03(0.75–1.42)

Stroke

No-exposed

145/3119

3.70

1 (Reference)

1 (Reference)

1 (Reference)

Uterine exposed

151/1777

6.94

1.47(1.13–1.92)

1.41(1.08–1.84)

1.37(1.05–1.79)

Childhood exposed

778/8848

7.27

1.10(0.77–1.57)

1.05(0.73–1.51)

1.04(0.72–1.48)

MI

No-exposed

39/3119

0.99

1 (Reference)

1 (Reference)

1 (Reference)

Uterine exposed

33/1777

1.47

1.18(0.69–2.02)

1.16(0.68–1.98)

1.15(0.68–1.97)

Childhood exposed

213/8848

1.94

1.07(0.54–2.12)

1.05(0.53–2.06)

1.05(0.53–2.06)

  1. Model 1: Adjusted for age, and gender
  2. Model 2: Included covariates in model 1 and further adjusted for education (junior high school or below, senior high school or above), smoking (current, never/former), drinking (current, never/former), and physical activity (current, never/former)
  3. Model 3: Included covariates in model 2 and further adjusted for low-density lipoprotein, hypertension, diabetes, use of antihypertensive medications, use of hypoglycemic medications, and use of hypolipidemic medications
  4. HR, hazard ratio; CI, confidence interval; IR, incidence rate; MI, myocardial infarction