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Table 1 Characteristics of participants in different BMI categories

From: What is an appropriate gestational weight gain for women with gestational diabetes mellitus: based on the adverse pregnancy outcomes of over 12 thousand participants?

Characteristic

Pre-pregnancy Body Mass Index

P-valuea

Underweight (BMI < 18.5)

Normal weight (BMI18.5 ~ 24.9)

Overweight (BMI25.0 ~ 29.9)

Obesity (BMI ≥ 30.0)

N

1180 (9.3)

9134 (71.9)

2097 (16.5)

301 (2.4)

 

Age(years)

30 (28–32)b

31 (29–34)c

32 (29–35)d

31 (29–34)cd

 < 0.001

  < 35

1020 (86.4)b

6852 (75.0)c

1501 (71.6)d

232 (77.1)cd

 < 0.001

  ≥ 35

160 (13.6)b

2282 (25.0)c

596 (28.4)d

69 (22.9)cd

Height(cm)

162.0 (160.0–165.0)b

162.0 (159.0–165.0)c

162.0 (159.0–165.0)c

162.0 (160.0–165.0)bc

 < 0.001

Pre-pregnancy Weight(kg)

46.0 (44.0–49.0)b

56.5 (52.5–60.0)c

70.0 (66.0–74.0)d

84.0 (79.5–90.0)e

 < 0.001

Pre-pregnancy BMI(kg/m2)

17.7 (17.0–18.1)b

21.6 (20.2–23.0)c

26.4 (25.6–27.6)d

31.4 (30.5–33.3)e

 < 0.001

Education level

    

 < 0.001

 Low

140 (11.9)b

1204 (13.2)b

365 (17.4)c

64 (21.3)c

 Medium

832 (70.5)b

6387 (69.9)b

1473 (70.2)b

214 (71.1)b

 High

194 (16.4)b

1415 (15.5)b

231 (11.0)c

20 (6.6)c

 Missing

14 (1.2)b

128 (1.4)b

28 (1.3)b

3 (1.0)b

Oral glucose tolerance test

 Fasting plasma glucose level(mmol/L)

5.11 (4.66–5.30)b

5.19 (4.88–5.40)c

5.29 (5.10–5.56)d

5.32 (5.13–5.58)d

 < 0.001

 1 h plasma glucose level(mmol/L)

9.05 ± 1.78b

9.24 ± 1.73c

9.64 ± 1.80d

9.79 ± 1.69d

 < 0.001

 2 h plasma glucose level(mmol/L)

7.89 ± 1.48b

7.96 ± 1.48b

8.07 ± 1.52c

7.78 ± 1.50b

0.001

History of adverse pregnancy

473 (40.1)b

4495 (49.2)c

1092 (52.1)c

154 (51.2)c

 < 0.001

History of previous cesarean section

131 (11.1)b

1550 (17.0)c

474 (22.6)d

65 (21.6)cd

 < 0.001

Parity

    

 < 0.001

 Nulliparous

859 (72.8)b

5583 (61.1)c

1207 (57.6)d

180 (59.8)cd

 Multiparous

321 (27.2)b

3551 (38.9)c

890 (42.4)d

121 (40.2)cd

Family history of diabetes

95 (8.1)b

875 (9.6)b

241 (11.5)c

51 (16.9)d

 < 0.001

Family history of hypertension

123 (10.4)b

1342 (14.7)c

370 (17.6)d

69 (22.9)d

 < 0.001

Delivery

 Weight(kg)

61.0 (57.0–65.0)b

70.0 (66.0–75.0)c

81.6 (77.0–87.0)d

94.0 (88.0–100.0)e

 < 0.001

 Total GWG (kg)

15.0 (12.0–18.0)b

14.0 (11.0–17.0)c

12.0 (9.0–15.0)d

10.0 (7.0–14.0)e

 < 0.001

 Gestational age (weeks)

39.0 ± 1.02bc

39.0 ± 1.03c

38.9 ± 1.04b

38.9 ± 1.11b

 < 0.001

 Birth weight (g)

3250 (3012–3500)b

3415 (3150–3690)c

3500 (3210–3800)d

3560 (3210–3900)d

 < 0.001

Biochemical indicators at the end of pregnancy

 HbA1c (%)

5.2 (5.0–5.5)b

5.3 (5.1–5.6)c

5.4 (5.1–5.7)d

5.5 (5.3–5.8)e

 < 0.001

 HbA1c (mmol/mol)

33 (31–37)

34 (32–38)

36 (32–39)

37 (34–40)

 

 Total cholesterol(mmol/L)

5.89 ± 1.15b

5.74 ± 1.18c

5.52 ± 1.13d

5.28 ± 1.14e

 < 0.001

 HDL(mmol/L)

1.75 ± 0.43b

1.71 ± 0.41c

1.65 ± 0.37d

1.61 ± 0.34d

 < 0.001

 LDL(mmol/L)

3.06 ± 0.74b

2.87 ± 0.75c

2.74 ± 0.73d

2.63 ± 0.73d

 < 0.001

 Triglycerides(mmol/L)

2.68 (2.14–3.45)b

3.02 (2.37–3.91)c

3.10 (2.45–4.01)c

3.12 (2.51–3.93)c

 < 0.001

Adverse outcomes

467 (39.6)b

5160 (56.5)c

1521 (72.5)d

241 (80.1)e

 < 0.001

 Gestational hypertension

10 (0.8)b

149 (1.6)b

91 (4.3)c

31 (10.3)d

 < 0.001

 Preeclampsia

10 (0.8)b

173 (1.9)b

107 (5.1)c

36 (12.0)d

 < 0.001

 Cesarean section

369 (31.3)b

4128 (45.2)c

1257 (59.9)d

204 (67.8)d

 < 0.001

 LGA

123 (10.4)b

1889 (20.7)c

645 (30.8)d

110 (36.5)d

 < 0.001

 SGA

39 (3.3)b

224 (2.5)b

40 (1.9)b

4 (1.3)b

0.049

  1. Categorical variables are expressed as counts (percentages) and the chi-square test is used. If the number of cases is less than 40, or the number of grids with an expected value of less than 5 > 25% of the total number of grids, then Fisher’s exact probability test is used
  2. HDL High Density Lipoprotein, LDL Low Density Lipoprotein, LGA Large for Gestational Age, SGA Small for Gestational Age
  3. aContinuous variable that meets the conditions of normality and homogeneity of variance is expressed as mean ± standard deviation, using analysis of variance, and LSD is used for pairwise comparison between groups; otherwise, a non-parametric test is used and expressed as the median (quartile)
  4. bcdeThere is no significant difference between groups with the same symbol
  5. P < 0.05 were considered statistically significant