Characteristic | Pre-pregnancy Body Mass Index | P-valuea | |||
---|---|---|---|---|---|
Underweight (BMI < 18.5) | Normal weight (BMI18.5 ~ 24.9) | Overweight (BMI25.0 ~ 29.9) | Obesity (BMI ≥ 30.0) | ||
N | 1180 (9.3) | 9134 (71.9) | 2097 (16.5) | 301 (2.4) | Â |
Age(years) | 30 (28–32)b | 31 (29–34)c | 32 (29–35)d | 31 (29–34)cd |  < 0.001 |
  < 35 | 1020 (86.4)b | 6852 (75.0)c | 1501 (71.6)d | 232 (77.1)cd |  < 0.001 |
  ≥ 35 | 160 (13.6)b | 2282 (25.0)c | 596 (28.4)d | 69 (22.9)cd | |
Height(cm) | 162.0 (160.0–165.0)b | 162.0 (159.0–165.0)c | 162.0 (159.0–165.0)c | 162.0 (160.0–165.0)bc |  < 0.001 |
Pre-pregnancy Weight(kg) | 46.0 (44.0–49.0)b | 56.5 (52.5–60.0)c | 70.0 (66.0–74.0)d | 84.0 (79.5–90.0)e |  < 0.001 |
Pre-pregnancy BMI(kg/m2) | 17.7 (17.0–18.1)b | 21.6 (20.2–23.0)c | 26.4 (25.6–27.6)d | 31.4 (30.5–33.3)e |  < 0.001 |
Education level |  |  |  |  |  < 0.001 |
 Low | 140 (11.9)b | 1204 (13.2)b | 365 (17.4)c | 64 (21.3)c | |
 Medium | 832 (70.5)b | 6387 (69.9)b | 1473 (70.2)b | 214 (71.1)b | |
 High | 194 (16.4)b | 1415 (15.5)b | 231 (11.0)c | 20 (6.6)c | |
 Missing | 14 (1.2)b | 128 (1.4)b | 28 (1.3)b | 3 (1.0)b | |
Oral glucose tolerance test | |||||
 Fasting plasma glucose level(mmol/L) | 5.11 (4.66–5.30)b | 5.19 (4.88–5.40)c | 5.29 (5.10–5.56)d | 5.32 (5.13–5.58)d |  < 0.001 |
 1 h plasma glucose level(mmol/L) | 9.05 ± 1.78b | 9.24 ± 1.73c | 9.64 ± 1.80d | 9.79 ± 1.69d |  < 0.001 |
 2 h plasma glucose level(mmol/L) | 7.89 ± 1.48b | 7.96 ± 1.48b | 8.07 ± 1.52c | 7.78 ± 1.50b | 0.001 |
History of adverse pregnancy | 473 (40.1)b | 4495 (49.2)c | 1092 (52.1)c | 154 (51.2)c |  < 0.001 |
History of previous cesarean section | 131 (11.1)b | 1550 (17.0)c | 474 (22.6)d | 65 (21.6)cd |  < 0.001 |
Parity |  |  |  |  |  < 0.001 |
 Nulliparous | 859 (72.8)b | 5583 (61.1)c | 1207 (57.6)d | 180 (59.8)cd | |
 Multiparous | 321 (27.2)b | 3551 (38.9)c | 890 (42.4)d | 121 (40.2)cd | |
Family history of diabetes | 95 (8.1)b | 875 (9.6)b | 241 (11.5)c | 51 (16.9)d |  < 0.001 |
Family history of hypertension | 123 (10.4)b | 1342 (14.7)c | 370 (17.6)d | 69 (22.9)d |  < 0.001 |
Delivery | |||||
 Weight(kg) | 61.0 (57.0–65.0)b | 70.0 (66.0–75.0)c | 81.6 (77.0–87.0)d | 94.0 (88.0–100.0)e |  < 0.001 |
 Total GWG (kg) | 15.0 (12.0–18.0)b | 14.0 (11.0–17.0)c | 12.0 (9.0–15.0)d | 10.0 (7.0–14.0)e |  < 0.001 |
 Gestational age (weeks) | 39.0 ± 1.02bc | 39.0 ± 1.03c | 38.9 ± 1.04b | 38.9 ± 1.11b |  < 0.001 |
 Birth weight (g) | 3250 (3012–3500)b | 3415 (3150–3690)c | 3500 (3210–3800)d | 3560 (3210–3900)d |  < 0.001 |
Biochemical indicators at the end of pregnancy | |||||
 HbA1c (%) | 5.2 (5.0–5.5)b | 5.3 (5.1–5.6)c | 5.4 (5.1–5.7)d | 5.5 (5.3–5.8)e |  < 0.001 |
 HbA1c (mmol/mol) | 33 (31–37) | 34 (32–38) | 36 (32–39) | 37 (34–40) |  |
 Total cholesterol(mmol/L) | 5.89 ± 1.15b | 5.74 ± 1.18c | 5.52 ± 1.13d | 5.28 ± 1.14e |  < 0.001 |
 HDL(mmol/L) | 1.75 ± 0.43b | 1.71 ± 0.41c | 1.65 ± 0.37d | 1.61 ± 0.34d |  < 0.001 |
 LDL(mmol/L) | 3.06 ± 0.74b | 2.87 ± 0.75c | 2.74 ± 0.73d | 2.63 ± 0.73d |  < 0.001 |
 Triglycerides(mmol/L) | 2.68 (2.14–3.45)b | 3.02 (2.37–3.91)c | 3.10 (2.45–4.01)c | 3.12 (2.51–3.93)c |  < 0.001 |
Adverse outcomes | 467 (39.6)b | 5160 (56.5)c | 1521 (72.5)d | 241 (80.1)e |  < 0.001 |
 Gestational hypertension | 10 (0.8)b | 149 (1.6)b | 91 (4.3)c | 31 (10.3)d |  < 0.001 |
 Preeclampsia | 10 (0.8)b | 173 (1.9)b | 107 (5.1)c | 36 (12.0)d |  < 0.001 |
 Cesarean section | 369 (31.3)b | 4128 (45.2)c | 1257 (59.9)d | 204 (67.8)d |  < 0.001 |
 LGA | 123 (10.4)b | 1889 (20.7)c | 645 (30.8)d | 110 (36.5)d |  < 0.001 |
 SGA | 39 (3.3)b | 224 (2.5)b | 40 (1.9)b | 4 (1.3)b | 0.049 |