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Table 3 Multivariate logistic regression revealed no significant variable directly affecting wound healing

From: Effects of vildagliptin on wound healing and markers of inflammation in patients with type 2 diabetic foot ulcer: a prospective, randomized, double-blind, placebo-controlled, single-center study

Characteristics

Ulcer unhealed

n = 36

Ulcer healed

n = 14

OR 95%CI Unadjusted P value

OR 95%CI Adjusted P value

Placebo

20 (55.5)

5 (35.7)

  

Vildagliptin

16 (44.4)

9 (64.3)

2.2 (0.6–8.0); 0.21

11.2 (1.1–113.5); 0.04

Microvascular complication*

30 (83)

10 (71)

0.5 (0.11–2.2); 0.43

0.9 (0.03–24.0); 0.90

Smoking

10(28)

2(14)

0.4 (0.08–2.3); 0.30

0.5 (0.03–8.8); 0.50

Amputation

16 (44)

6 (42)

1.0 (0.3–3.2); 1.00

0.7 (0.04–11.5); 0.20

Dyslipidaemia

27 (75)

8 (57)

0.4 (0.1–1.6); 0.20

0.2 (0.02–2.3); 0.20

Peripheral vascular disease

10 (28)

5 (35)

0.7 (0.2–2.6); 0.60

0.3 (0.3–3.3); 0.33

Years of diabetes

19.3 ± 10.0

21.2 ± 7.5

1.0 (0.9–1.1) 0.60

0.9 (0.8–1.1); 0.70

  1. *Microvascular complication included retinopathy, nephropathy, neuropathy