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Table 4 Multinomial logistic regression model for the association of TyG index quartiles with elevated blood pressure, pre-hypertension, and hypertension by age, sex, BMI, and insulin resistance status

From: Association between the triglyceride-glucose (TyG) index and increased blood pressure in normotensive subjects: a population-based study

  

Quartile of TyG index

P interaction

Quartile 1

Quartile 2

Quartile 3

Quartile 4

By age

      

 Elevated BP

     

0.387

  Age < 50 years

No. of cases

111

89

100

106

 
 

OR (95% CI)

1.00 (ref.)

0.87 (0.65–1.17)

1.10 (0.82–1.48)

1.28 (0.94–1.76)

 

  Age ≥ 50 years

No. of cases

99

158

206

189

 
 

OR (95% CI)

1.00 (ref.)

1.19 (0.90–1.57)

1.54 (1.17–2.02)

1.66 (1.25–2.21)

 

 Pre-HTN

     

 < 0.001

  Age < 50 years

No. of cases

360

442

575

748

 
 

OR (95% CI)

1.00 (ref.)

1.30 (1.11–1.53)

1.88 (1.60–2.20)

2.64 (2.23–3.12)

 

  Age ≥ 50 years

No. of cases

219

332

525

547

 
 

OR (95% CI)

1.00 (ref.)

1.08 (0.88–1.33)

1.56 (1.28–1.91)

1.76 (1.43–2.16)

 

 HTN

     

 < 0.001

  Age < 50 years

No. of cases

56

121

195

436

 
 

OR (95% CI)

1.00 (ref.)

2.00 (1.43–2.78)

3.15 (2.29–4.34)

6.68 (4.88–9.13)

 

  Age ≥ 50 years

No. of cases

105

218

302

409

 
 

OR (95% CI)

1.00 (ref.)

1.52 (1.17–1.98)

1.95 (1.51–2.52)

2.84 (2.20–3.68)

 

By sex

      

 Elevated BP

     

0.015

  Male

No. of cases

86

113

126

169

 
 

OR (95% CI)

1.00 (ref.)

0.98 (0.72–1.34)

0.98 (0.72–1.33)

1.32 (0.98–1.79)

 

  Female

No. of cases

124

134

180

126

 
 

OR (95% CI)

1.00 (ref.)

1.02 (0.78–1.32)

1.52 (1.17–1.97)

1.56 (1.17–2.08)

 

 Pre-HTN

      

  Male

No. of cases

227

368

649

912

0.464

 

OR (95% CI)

1.00 (ref.)

1.11 (0.91–1.36)

1.60 (1.32–1.94)

2.03 (1.67–2.46)

 

  Female

No. of cases

352

406

451

383

 
 

OR (95% CI)

1.00 (ref.)

1.27 (1.08–1.49)

1.75 (1.48–2.06)

2.29 (1.90–2.75)

 

 HTN

     

0.453

  Male

No. of cases

63

144

267

576

 
 

OR (95% CI)

1.00 (ref.)

1.47 (1.06–2.03)

2.11 (1.55–2.86)

3.91 (2.90–5.27)

 

  Female

No. of cases

98

195

230

269

 
 

OR (95% CI)

1.00 (ref.)

1.88 (1.45–2.45)

2.40 (1.85–3.12)

3.97 (3.04–5.19)

 

By BMI

      

 Elevated BP

     

0.475

  BMI < 25.0 kg/m2

No. of cases

168

182

204

153

 
 

OR (95% CI)

1.00 (ref.)

1.03 (0.82–1.29)

1.43 (1.14–1.79)

1.56 (1.22–2.00)

 

  BMI ≥ 25.0 kg/m2

No. of cases

41

65

101

141

 
 

OR (95% CI)

1.00 (ref.)

1.09 (0.71–1.67)

1.14 (0.76–1.70)

1.51 (1.02–2.23)

 

 Pre-HTN

     

0.598

  BMI < 25.0 kg/m2

No. of cases

463

554

676

571

 
 

OR (95% CI)

1.00 (ref.)

1.23 (1.07–1.41)

1.86 (1.62–2.15)

2.19 (1.88–2.56)

 

  BMI ≥ 25.0 kg/m2

No. of cases

115

217

423

722

 
 

OR (95% CI)

1.00 (ref.)

1.27 (0.96–1.67)

1.67 (1.30–2.16)

2.45 (1.91–3.14)

 

 HTN

      

  BMI < 25.0 kg/m2

No. of cases

130

213

271

349

 
 

OR (95% CI)

1.00 (ref.)

1.50 (1.18–1.90)

2.25 (1.78–2.83)

3.94 (3.12–4.97)

0.698

  BMI ≥ 25.0 kg/m2

No. of cases

30

124

225

496

 
 

OR (95% CI)

1.00 (ref.)

2.75 (1.79–4.24)

3.27 (2.16–4.95)

6.26 (4.18–9.36)

 

By insulin resistance statusa

      

 Elevated BP

     

0.749

  HOMA-IR < 2.5

No. of cases

59

58

64

39

 
 

OR (95% CI)

1.00 (ref.)

0.92 (0.61–1.37)

1.18 (0.78–1.78)

1.03 (0.64–1.66)

 

  HOMA-IR ≥ 2.5

No. of cases

7

6

12

39

 
 

OR (95% CI)

1.00 (ref.)

0.34 (0.09–1.26)

0.41 (0.13–1.32)

0.83 (0.29–2.40)

 

 Pre-HTN

     

0.679

  HOMA-IR < 2.5

No. of cases

138

189

222

153

 
 

OR (95% CI)

1.00 (ref.)

1.47 (1.14–1.90)

2.00 (1.53–2.61)

1.86 (1.37–2.52)

 

  HOMA-IR ≥ 2.5

No. of cases

9

39

68

167

 
 

OR (95% CI)

1.00 (ref.)

1.91 (0.80–4.54)

1.71 (0.74–3.96)

2.53 (1.12–5.74)

 

 HTN

     

0.067

  HOMA-IR < 2.5

No. of cases

43

71

85

105

 
 

OR (95% CI)

1.00 (ref.)

1.49 (0.98–2.27)

1.92 (1.26–2.91)

3.16 (2.06–4.86)

 

  HOMA-IR ≥ 2.5

No. of cases

6

18

35

84

 
 

OR (95% CI)

1.00 (ref.)

1.15 (0.39–3.40)

0.98 (0.35–2.78)

1.36 (0.50–3.73)

 
  1. Adjusted for survey year, age, sex, marital status, education level, household income quartiles, smoking status, and frequency of heavy episodic drinking, family history of hypertension, and BMI, except for the variable used in each stratified analysis
  2. TyG triglyceride and glucose, BP blood pressure, OR odds ratio, CI confidence interval, HTN hypertension, BMI body mass index, HOMA-IR homeostatic model assessment for insulin resistance
  3. aOnly 3,945 subjects with available data on HOMA-IR were analyzed