Table 3 Independent predictors of composite MACCEs

HGI group

 < 0.001

0.012

 Q5

Ref.

Ref.

Ref.

Ref.

 Q4

0.864 (0.778, 0.960)

0.007

0.889 (0.799, 0.989)

0.030

 Q3

0.789 (0.708, 0.878)

 < 0.001

0.861 (0.771, 0.960)

0.007

 Q2

0.746 (0.670, 0.831)

 < 0.001

0.835 (0.747, 0.932)

0.001

 Q1

0.858 (0.773, 0.952)

0.004

0.929 (0.833, 1.035)

0.173

Age, years

1.020 (1.017, 1.024)

 < 0.001

1.011 (1.006, 1.016)

 < 0.001

Male gender

0.985 (0.917, 1.058)

0.686

Medical history

 Current/ex-Smoker

1.018 (0.950, 1.090)

0.614

 Hypertension

1.239 (1.146, 1.339)

 < 0.001

1.109 (1.022, 1.204)

0.013

 Diabetes

1.309 (1.222, 1.403)

 < 0.001

 Dyslipidemia

0.972 (0.907, 1.041)

0.415

 Previous Stroke

1.375 (1.265, 1.495)

 < 0.001

1.208 (1.109, 1.317)

 < 0.001

 Previous MI

1.369 (1.239, 1.512)

 < 0.001

 Past PCI

1.372 (1.256, 1.499)

 < 0.001

1.268 (1.157, 1.389)

 < 0.001

 Past CABG

1.232 (1.005, 1.511)

0.045

Physical examination

 BMI, kg/m²

0.984 (0.975, 0.994)

0.001

0.987 (0.977, 0.997)

0.012

 SBP, mmHg

1.003 (1.002, 1.005)

 < 0.001

 DBP, mmHg

0.996 (0.993, 0.999)

0.01

 Heart rate, bpm

1.008 (1.005, 1.010)

 < 0.001

1.004 (1.002, 1.007)

0.001

Clinical presentation

 STEMI

1.042 (0.954, 1.139)

0.357

 NSTEMI

1.407 (1.295, 1.530)

 < 0.001

1.205 (1.068, 1.358)

 < 0.001

 UAP

0.779 (0.726, 0.835)

 < 0.001

Medication on admission

 Antiplatelet agent

1.070 (0.998, 1.148)

0.057

 ACEI/ARB

1.107 (1.031, 1.189)

0.005

 Beta-blocker

0.989 (0.911, 1.073)

0.783

 Statins

0.983 (0.912, 1.059)

0.649

Laboratory data

 WBC, 10⁹/L

1.024 (1.010, 1.037)

0.001

1.020 (1.004, 1.036)

0.008

 Hemoglobin, g/L

0.992 (0.990, 0.994)

 < 0.001

 Hs-CRP, mg/L

1.013 (1.010, 1.016)

 < 0.001

 RBG at admission, mmol/L

1.023 (1.014, 1.032)

 < 0.001

 FPG, mmol/L

1.048 (1.034, 1.062)

 < 0.001

 HbA1c,%

1.077 (1.053, 1.102)

 < 0.001

 Albumin, g/L

0.954 (0.946, 0.962)

 < 0.001

 Creatinine, umol/L

1.002 (1.001, 1.002)

 < 0.001

 eGFR, ml/min/1.73m²

0.988 (0.987, 0.990)

 < 0.001

0.993 (0.991, 0.995)

 < 0.001

 TC, mmol/L

0.949 (0.918, 0.982)

0.002

 TGs, mmol/L

0.986 (0.958, 1.016)

0.361

 LDL-C, mmol/L

0.952 (0.909, 0.997)

0.035

 HDL-C, mmol/L

0.745 (0.653, 0.850)

 < 0.001

0.809 (0.681, 0.962)

0.002

Echocardiography

 LVEF

0.107 (0.076, 0.148)

 < 0.001

0.240 (0.167, 0.346)

 < 0.001

Angiography findings

 LM/three-vessel

1.233 (1.150, 1.321)

 < 0.001

1.208 (1.117, 1.307)

 < 0.001

 Proximal LAD

0.917 (0.855, 0.983)

0.014

0.914 (0.848, 0.986)

0.019

Medication during hospitalization

 PCI/CABG

1.058 (0.987, 1.133)

0.111

 Antiplatelet agent

0.774 (0.679, 0.882)

 < 0.001

0.806 (0.693, 0.937)

0.020

 ACEI/ARB

1.096 (1.022, 1.174)

0.010

 Beta-blocker

1.040 (0.965, 1.121)

0.301

 Statins

0.842 (0.756, 0.937)

0.002

Hypoglycemic agents

 Alpha-glucosidase inhibitor

1.198 (1.108, 1.296)

 < 0.001

 Metformin

1.056 (0.954, 1.168)

0.293

 Sulfonylurea

0.994 (0.876, 1.128)

0.925

 DPP-4i

1.165 (0.437, 3.107)

0.760

 Insulin

1.352 (1.208, 1.512)

 < 0.001

 Insulin sensitizer

1.014 (0.814, 1.263)

0.901