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Table 4 Predictive value of eGDR for MACCE and each component in univariate and multivariate analysis

From: Predictive worth of estimated glucose disposal rate: evaluation in patients with non-ST-segment elevation acute coronary syndrome and non-diabetic patients after percutaneous coronary intervention

 

Univariate analysis

Multivariate analysisa

HR

95% CI

P value

HR

95% CI

P value

eGDR as a nominal variableb

 MACCE

1.688

1.330–2.093

 < 0.001

1.557

1.124–2.158

0.008

 All-cause death

1.114

0.453–2.742

0.814

0.518

0.135–1.982

0.337

 Non-fatal MI

1.246

0.764–2.033

0.377

1.140

0.580–2.241

0.704

 Non-fatal ischemic stroke

2.898

1.225–6.853

0.015

0.819

0.260–2.584

0.734

 Ischemia-driven revascularization

1.722

1.298–2.285

 < 0.001

2.158

1.394–3.342

0.001

eGDR as a continuous variablec

 MACCE

1.194

1.131–1.260

 < 0.001

1.337

1.201–1.488

 < 0.001

 All-cause death

1.074

0.871–1.325

0.504

0.776

0.520–1.158

0.214

 Non-fatal MI

1.110

0.990–1.245

0.075

1.279

1.027–1.594

0.028

 Non-fatal ischemic stroke

1.444

1.173–1.779

0.001

1.791

0.997–3.219

0.051

 Ischemia-driven revascularization

1.188

1.112–1.270

 < 0.001

1.363

1.190–1.561

 < 0.001

  1. eGDR estimated glucose disposal rate, MACCE major adverse cardio-cerebral events, HR hazard ratio, CI confidence interval, MI myocardial infarction
  2. aThe multivariate analysis was performed by using Model 4
  3. bThe HR was evaluated regarding the higher median of eGDR as reference
  4. cThe HR was evaluated by per 1-unit decrease of eGDR