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Table 3 Clinical and Glycemic variable inter groups studied at baseline, 3, and 6 months

From: Comparison of three insulin bolus calculators to increase time in range of glycemia in a group of poorly controlled adults Type 1 diabetes in a Brazilian public health service

  

Mean ± SD

p1

  

Baseline

3 months

6 months

Combo

x CSII

Glic

x CSII

Glic

x Combo

IB

CSII

24.27 ± 8.41

24.97 ± 10.32

24.06 ± 7.68

   

COMBO

28.03 ± 8.54

26.44 ± 8.69

25.56 ± 8.38

0.022

0.362

0.251

Glic

25.68 ± 8.14

25.13 ± 6.51

24.26 ± 7.07

   

SBP

CSII

114.18 ± 13.12

112.53 ± 12.01

112.85 ± 12.5

   

COMBO

123.59 ± 12.46

118.84 ± 11.25

113.56 ± 12.93

0.030

0.722

0.322

Glic

119.08 ± 15.34

113.82 ± 12.34

112.71 ± 9.1

   

TIR

CSII

40.4% ± 11.3%

39.4% ± 10.3%

39.3% ± 10.5%

   

COMBO

28.9% ± 11.9%

40.5% ± 11.8%

38.3% ± 12.7%

 < 0.001

0.002

0.116

Glic

27.9% ± 13.4%

33.9% ± 13.8%

36.3% ± 15.1%

   

AG

CSII

197.65 ± 28.1

197.12 ± 34.23

197.38 ± 30.43

   

COMBO

224.51 ± 49.64

204.38 ± 38.98

209.75 ± 40.92

0.064

0.277

0.435

Glic

216.4 ± 38.89

205.32 ± 42.45

203.85 ± 44.99

   

Bolus

CSII

26.15 ± 11.89

29.48 ± 11.31

28.03 ± 9.63

   

COMBO

26.16 ± 10.34

26.31 ± 11.79

29.69 ± 12.66

0.354

0.029

0.289

Glic

28.47 ± 11.58

24.29 ± 9.84

27.53 ± 11.47

   

WC

COMBO

82.88 ± 11.13

85.69 ± 11.06

87.34 ± 11.67

  

0.011

Glic

82.81 ± 9.5

83.08 ± 9.07

83.89 ± 9.31

  

A1c

CSII

9.0% ± 0.5%

8.6% ± 0.6%

8.6% ± 0.8%

   

COMBO

9.9% ± 1.3%

8.9% ± 1.2%

8.8% ± 1.3%

0.053

0.931

0.050

Glic

9.6% ± 1.5%

9.2% ± 1.8%

9.0% ± 1.4%

   
  1. CSII: Continuous Subcutaneous Insulin Infusion, A1c: Glycated Hemoglobin, Basal: Insulin basal rate, WC: Waist Circumference, SBP: Systolic Blood Pressure, TGT: Time on Glycemic Target, SD: Standard Deviation, AG: Average Glucose
  2. p1 = refers to nonparametric ANOVA with two way about the comparison between baseline time and 6 months between groups