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Table 2 Comparative clinical and glycemic variable intra groups studied at baseline, 3, and 6 intervention months

From: Comparison of three insulin bolus calculators to increase time in range of glycemia in a group of poorly controlled adults Type 1 diabetes in a Brazilian public health service

Variable

Baseline

Mean ± SD

Intervention period

3 months

6 months

0 × 3 months

3 × 6 months

0 × 6 months

CSII group (n = 35)

 Basal

24.7 ± 8.41

24.97 ± 10.32

24.06 ± 22,90

–

–

0.731 (p2)

 SBP

114.18 ± 13.12

112,53 ± 12.01

112.85 ± 12.50

–

–

0.712 (p2)

 Weight

67.84 ± 10.6

68.19 ± 12.38

68.47 ± 11.67

–

–

0.523 (p2)

 A1c

9% ± 0.5%

8.6% ± 0.6%

8.6% ± 0.8%

0.005

0.858

0.010

 TIR

40.0% ± 11.3%

39.4% ± 10.3%

39.3% ± 10.5%

0.596

0.950

0.573

 AG

197.6 ± 28.1

197.1 ± 34.2

197.4 ± 30.4

0.917

0.963

0.963

 SD

91.2 ± 13.2

90.9 ± 17.4

91.0 ± 13.9

0.912

0.977

0.944

 Hipo < 70

6.5% ± 7.6%

7.1% ± 6.8%

5.8% ± 5.0%

0.402

0.369

0.902 (p2)

Combo group (n = 33)

 Basal

28.03 ± 8.54

26.44 ± 8.69

25.56 ± 8.38

0.062

0.111

0.010

 SBP

123.59 ± 12.46

118.84 ± 11.25

113.56 ± 12.93

0.061

0.058

 < 0.001

 Weight

70.46 ± 13.93

71.2 ± 14.39

71.83 ± 14.77

0.056

0.037

0.007

 WC

82.88 ± 11.13

85.69 ± 11.06

87.34 ± 11.67

 < 0.001

0.017

 < 0.001

 A1c

9.9% ± 1.3%

8.9% ± 1.2%

8.8% ± 1.3%

 < 0.001

0.221

 < 0.001

 TIR

28.9% ± 11.9%

40.5% ± 11.8%

38.3% ± 12.7%

 < 0.001

0.193

 < 0.001

 AG

224.51 ± 49.64

204.38 ± 38.98

209.75 ± 40.92

0.005

0.190

0.012

 SD

100.9 ± 28.1

96.8 ± 21.9

96.4 ± 20.6

0.395

0.906

0.191

 Hipo < 70

6.0% ± 7.2%

6.3% ± 4.8%

5.9% ± 3.9%

0.462

0.395

0.673 (p2)

Glic group (n = 43)

 Basal

25.68 ± 8.14

25.13 ± 6.51

24.26 ± 7,07

–

–

0.229 (p2)

 SBP

119.08 ± 1.34

113.82 ± 12.34

112.71 ± 9.10

–

–

0.125 (p2)

 Weight

67.10 ± 11.68

67.03 ± 11.03

67.16 ± 10.94

–

–

0.911 (p2)

 WC

82.81 ± 9.50

83.08 ± 9.07

83.89 ± 9.31

–

–

0.260 (p2)

 A1c

9.6% ± 1.5%

9.2% ± 1.8%

9.0% ± 1.4%

0.001

0.065

 < 0.001

 TIR

27.9% ± 13.4%

33.9% ± 13.8%

36.3% ± 15.1%

0.003

0.200

 < 0.001

 AG

216.4 ± 38.89

205.32 ± 42.45

203.85 ± 44.99

0.016

0.810

0.039

 SD

100.3 ± 23.24

92.17 ± 22.36

90.61 ± 24.16

0.002

0.648

0.033

 Hipo < 70

5.6% ± 5.5%

6.1% ± 4.3%

6.6% ± 5.1%

0.426

0.939

0.437 (p2)

  1. CSII: Continuous Subcutaneous Insulin Infusion, A1c: Glycated Hemoglobin, Basal: Insulin basal rate, WC: Waist Circumference, SBP: Systolic Blood Pressure, TGT: Time on Glycemic Target, SD: Standard Deviation, AG: Average Glucose
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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