Table 4 Prevalence of celiac disease predisposing alleles and their configurations in Lower Silesia children with type 1 diabetes
From: Prevalence of haplotype DQ2/DQ8 and celiac disease in children with type 1 diabetes
Allele: | I | II | P | OR (95% CI) |
|---|---|---|---|---|
T1D | T1D + CD | |||
N = 150 | N = 16 | |||
HLA DQ2.2 | 23 (15.3%) | 3 (18,8%) | 0.5283 | 1.27 (0.34–4.84) |
HLA DQ2.5 | 75 (50.0%) | 13 (81,3%) | 0.0220 | 1.0 (0.43–2.30) |
HLA DQ8 | 93 (62.0%) | 13 (81,3%) | 0.0921 | 0.61 (0.27–1.41) |
HLA DQ2.2/DQ2.5 | 6 (4.0%) | 2 (12.5%) | 0.4355 | 3.43 (0.63–18.61) |
HLA DQ2.2/DQ8 | 12 (8.0%) | 1 (6.25%) | 0.5980 | 0.77 (0.09–6.31) |
HLA DQ2.5/DQ8 | 36 (24.0%) | 10 (62.5%) | 0.0045 | 5.28 (1.79–15.53) |
HLA DQ2.2 only | 5 (3.3%) | 0 | 0.6665 | 0.80 (0.04–15.16) |
HLA DQ2.5 only | 29 (19.3%) | 1 (6,3%) | 0.3061 | 0.28 (0.03–2.19) |
HLA DQ8 only | 42 (28.0%) | 2 (12,5%) | 0.1257 | 0.37 (0.08–1.67) |
HLA DQ2/DQ8 negative | 20 (13.3%) | 0 | < 0.0001 | 0.19 (0.11–3.34) |