At baseline | At 13 years follow-up | |||||
---|---|---|---|---|---|---|
Routine | Intensive | N | Routine | Intensive | N | |
n | 169 | 242 | 169 | 242 | ||
Female sex | 59 (34.9) | 84 (34.7) | 411 | 59 (34.9) | 84 (34.7) | 411 |
Age at inclusion (years) | 58 (6.8) | 58 (6.5) | 411 | 58 (6.8) | 58 (6.5) | 411 |
Age at follow-up (years) | 71 (6.72) | 70 (6.63) | 411 | |||
Follow-up time (years) | 12.6 (1.41) | 12.5 (1.42) | 411 | |||
BMI (kg/m2) | 31 (4.9) | 30 (5.3) | 399 | 30 (5.2) | 30 (5.8) | 410 |
Waist (cm) | 104.7 (12.2) | 104 (12.8) | 399 | 105 (13.2) | 106 (14.2) | 407 |
Systolic blood pressure (mmHg) | 148.3 (19.3) | 145.6 (16.8) | 399 | 141.2 (16.3) | 137.4 (15.5) | 410 |
Diastolic blood pressure (mmHg) | 88.1 (10.6) | 87.6 (9.6) | 399 | 83.6 (9.9) | 82.0 (9.3) | 410 |
HbA1c (%) | 6.7 (1.4) | 6.9 (1.6) | 395 | 6.7 (0.9) | 6.9 (0.9) | 410 |
HbA1c (mmol/mol) | 50 (15) | 52 (17) | 395 | 50 (10) | 52 (10) | 410 |
Total cholesterol (mmol/L) | 5.8 (1.2) | 5.7 (1.1) | 384 | 4.4 (1.0) | 4.3 (1.0) | 410 |
Triglycerides (mmol/L) | 1.97 (1.3) | 1.95 (1.3) | 377 | 1.69 (0.7) | 1.82 (0.9) | 410 |
HDL cholesterol (mmol/L) | 1.39 (0.3) | 1.38 (0.4) | 374 | 1.38 (0.4) | 1.37 (0.4) | 410 |
LDL cholesterol (mmol/L) | 3.45 (1.0) | 3.45 (1.0) | 362 | 2.26 (0.8) | 2.16 (0.8) | 398 |
Albumine Creatinine ratio (mg/g) | 2.95 (10.5) | 1.88 (4.2) | 372 | 8.31 (37.1) | 5.89 (20.3) | 406 |
Any glucose-lowering drug | s | – | 411 | 106 (72.6) | 149 (77.6) | 338 |
Metformin | – | – | 411 | 91 (62.3) | 131 (68.2) | 338 |
Insulin | – | – | 411 | 24 (16.4) | 36 (18.8) | 338 |
Sulphonylurea | – | – | 411 | 10 (6.8) | 16 (8.3) | 338 |
Antihypertensives | 62 (36.7) | 79 (32.6) | 411 | 120 (82.2) | 165 (85.9) | 338 |
ACE/ARB blockers | 25 (14.8) | 37 (15.3) | 411 | 101 (69.2) | 147 (76.6) | 338 |
Betablockers | 24 (14.2) | 32 (13.2) | 411 | 39 (26.7) | 50 (26.0) | 338 |
Calcium antagonists | 17 (10.1) | 21 (8.7) | 411 | 57 (39.0) | 69 (35.9) | 338 |
Diuretics | 35 (20.7) | 41 (16.9) | 411 | 66 (45.2) | 105 (54.7) | 338 |
Statins | 21 (12.4) | 35 (14.5) | 411 | 113 (77.4) | 155 (80.7) | 338 |
Aspirin | 15 (8.9) | 24 (9.9) | 411 | 66 (45.2) | 119 (62.0) | 338 |
Smoking | 407 | 379 | ||||
Non-smoker | 56 (33.7) | 101 (41.9) | 54 (34.2) | 90 (40.7) | ||
Former smoker | 63 (38.0) | 81 (33.6) | 79 (50.0) | 104 (47.1) | ||
Current smoker | 47 (28.3) | 59 (24.5) | 25 (15.8) | 27 (12.2) | ||
Alcohol use * | 47 (29.2) | 66 (29.9) | 382 | 7.7 (8.9) | 7.7 (9.0) | 308 |