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Table 3 The patients’ characteristics in subjects with MAFLD-related Profiles 2

From: MAFLD associated with COPD via systemic inflammation independent of aging and smoking in men

 

Profile 2  < 50 years old and MAFLD

Median (IQR)

Range (min–max)

Number

37.6% (768/2041)

N/A

Age

43 (39–47)

21–49

Body mass index (kg/m2)

25.9 (24.4–28.2)

18.4–137.5

Waist circumference (cm)

91.5 (87–97.5)

71–123.5

Visceral adiposity (Presence/Absence)

59.0%/41.0% (453/315)

N/A

Systolic blood pressure (mmHg)

120 (110–128)

89–190

Diastolic blood pressure (mmHg)

78 (70–84)

48–134

Type 2 diabetes mellitus (Presence/Absence)

7.9%/92.1% (61/707)

N/A

Hypertension (Presence/Absence)

36.1%/63.9% (277/491)

N/A

Hypertriglyceridemia (Presence/Absence)

48.9%/51.1% (375/393)

N/A

Depressed HDL-cholesterol (Presence/Absence)

15.8%/84.2% (121/647)

N/A

Alcohol intake habit (None/Yes)

33.4%/66.6% (257/511)

N/A

Dairy alcohol consumption (None/1–19 g/20–39 g/40–59 g)

33.5%/19.9%/29.8%/16.8% (257/153/229/129)

N/A

Presence or past smoking habit (Yes/No)

70.2%/29.8% (539/229)

N/A

Pack years (Sum of past and present)

10 (0–22.5)

0–100

Pack year ≥ 60 (Yes/No)

3.5%/96.5% (57/1564)

N/A

Pulmonary functions

 %VC

107.5 (98.0–117.2)

70.6–155.5

 FEV1%

80.7 (77.0–84.0)

54.4–98.1

 %FEV1

93.2 (85.6–101.2)

48.6–134.4

 Prevalence of COPD (Presence/Absence)

13.6%/86.4% (105/663)

N/A

Biochemical examinations

 Red blood cell count (× 104/µL)

508 (483–531)

396–657

 Hemoglobin (g/dL)

15.5 (14.8–16.1)

12.0–18.7

 Hematocrit (%)

45.2 (43.5–46.9)

36.4–56.2

 White blood cell count (/µL)

6,050 (5100–7000)

3000–13,600

 Platelet count (× 104/µL)

24.4 (21.5–27.6)

7.3–51.5

 AST (U/L)

24 (19–30)

6–164

 ALT (U/L)

34 (24–51)

8–277

 Lactate dehydrogenase (U/L)

165 (151–182)

84–431

 ALP (U/L)

209 (182–248)

73–506

 GGT (U/L)

43 (29–68)

10–449

 Total protein (g/dL)

7.2 (7.0–7.4)

5.9–8.4

 Cholinesterase (U/L)

384 (346–427)

208–613

 Albumin (g/dL)

4.6 (4.4–4.7)

3.1–5.2

 Total bilirubin (mg/dL)

0.7 (0.6–0.9)

0.2–3.0

 Total cholesterol (mg/dL)

207 (186–229)

120–357

 HDL-cholesterol (mg/dL)

49 (43–57)

24–164

 LDL-cholesterol (mg/dL)

131 (114–152)

54–262

 Triglycerides (mg/dL)

136 (93–201)

31–1233

 Fasting glucose (mg/dL)

98 (93–104)

77–312

 HbA1c (%)

5.6 (5.4–5.8)

4.5–12.6

 CRP (mg/dL)

0.1 (0.08–0.15)

0.01–3.39

 BUN (mg/dL)

12.8 (11.0–14.9)

6.5–26.3

 Creatinine (mg/dL)

0.8 (0.73–0.9)

0.48–2.4

 eGFR (mL/min/1.73 m2)

85.1 (76.3–94.1)

25.3–142.6

 Uric acid (mg/dL)

6.5 (5.6–7.3)

0.8–11.9

 Sodium (mmol/L)

141 (140–142)

136–146

 Potassium (mmol/L)

4.2 (4.0–4.3)

3.3–5.3

 Chloride (mmol/L)

105 (104–107)

98–110

 CRP/Albumin ratio

0.0222 (0.020–0.032)

0.002–0.892

 FIB-4 index

0.725 (0.578–0.911)

0.281–5.214

  1. COPD chronic obstructive pulmonary disease, MAFLD metabolic associated fatty liver disease, VC vital capacity, HDL-cholesterol high-density lipoprotein-cholesterol, FEV forced expiratory volume, FVC forced vital capacity, AST aspartate aminotransferase, ALT alanine aminotransferase, GGT γ-glutamyl transpeptidase, LDL-cholesterol low-density lipoprotein-cholesterol, HbA1c hemoglobin A1c, CRP C-reactive protein, BUN blood urea nitrogen, GFR glomerular filtration rate, FIB-4 fibrosis-4