Table 5 Association between clinical and biochemical parameters with the CD36 gene methylation

rs1761667

Body mass index (0/1)

0.09 [0.64–1.75]; 0.82

1.31 [0.99–1.74]; 0.06

0.78 [0.34–1.82]; 0.57

Waist size (0/1)

0.90 [0.72–1.13]; 0.37

0.80 [0.65–0.98]; 0.03*

0.81 [0.60–1.09]; 0.17

Percent body fat (0/1)

0.94 [0.70–1.24]; 0.65

1.41 [0.94–2.12]; 0.09

0.70 [0.36–1.35]; 0.28

Visceral fat level (0/1)

1.54 [0.65–3.65]; 0.33

0.62 [0.34–1.14]; 0.12

3.44 [0.45–26.60]; 0.24

HbA₁c (0/1)

0.32 [0.04–2.57]; 0.28

1.26 [0.35–4.57]; 0.72

0.67 [0.35–1.29]; 0.23

IR-HOMA (0/1)

0.71 [0.40–1.26]; 0.24

0.82 [0.53–1.27]; 0.38

0.95 [0.87–1.05]; 0.34

sCD36

1.00 [0.99–1.00]; 0.56

1.00 [0.99–1.00]; 0.64

1.00 [0.99–1.00]; 0.37

Dnmt3a

1.05 [0.99–1.11]; 0.11

1.01 [0.98–1.03]; 0.61

0.96 [0.89–1.02]; 0.19

Total cholesterol (0/1)

0.05 [0.00–59.94]; 0.41

0.13 [0.00–105.51]; 0.56

0.00 [0.00–2.98]; 0.09

HDL cholesterol (0/1)

0.22 [0.00–14.01]; 0.47

1.14 [0.01–100.15]; 0.91

0.02 [0.00–1.06]; 0.048*

LDL cholesterol (0/1)

0.40 [0.08–1.96]; 0.26

0.91 [0.21–3.89]; 0.52

0.81 [0.28–2.36]; 0.70

Triglycerides (0/1)

0.40 [0.06–2.53]; 0.33

0.29 [0.04–1.93]; 0.20

4.45 [0.30–6.93]; 0.64

rs3211867

Body mass index (0/1)

1.58 [0.90–2.78]; 0.11

1.12 [0.86–1.45]; 0.83

0.62 [0.32–1.20]; 0.16

Waist size (0/1)

0.92 [0.71–1.18]; 0.49

0.11 [0.93–1.31]; 0.25

0.99 [0.75–1.31]; 0.94

Percent body fat (0/1)

1.11 [0.84–1.46]; 0.46

0.80 [0.54–1.19]; 0.27

0.97 [0.55–1.72]; 0.92

Visceral fat level (0/1)

0.76 [0.30–1.89]; 0.55

0.97 [0.52–1.81]; 0.92

3.72 [0.90–15.33]; 0.07

HbA₁c (0/1)

4.93 [0.29–84.02]; 0.27

0.80 [0.25–2.57]; 0.71

1.97 [0.75–5.15]; 0.17

IR-HOMA (0/1)

0.41 [0.19–0.91]; 0.03*

1.12 [0.77–1.62]; 0.55

0.98 [0.90–1.07]; 0.63

sCD36

0.99 [0.99–1.00]; 0.62

1.00 [0.99–1.00]; 0.75

1.00 [0.99–1.00]; 0.39

Dnmt3a

0.99 [0.94–1.03]; 0.55

1.01 [0.98–1.03]; 0.65

0.97 [0.90–1.04]; 0.35

Total cholesterol (0/1)

0.16 [0.00–877.66]; 0.67

0.55 [0.00–506.55]; 0.86

0.21 [0.00–2.98]; 0.09

HDL cholesterol (0/1)

14.29 [0.18–1115.17]; 0.23

56.21 [0.50–6279.58]; 0.09

21.01 [0.25–1718.01]; 0.17

LDL cholesterol (0/1)

0.56 [0.11–2.75]; 0.47

1.36 [0.33–5.62]; 0.66

3.66 [0.85–15.84]; 0.08

Triglycerides (0/1)

2.39 [0.01–58.43]; 0.59

13.80 [0.31–605.36]; 0.17

1.40 [0.02–92.94]; 0.23

rs1527483

Body mass index (0/1)

0.33 [0.08–1.26]; 0.11

–

0.89 [0.56–1.42]; 0.62

Waist size (0/1)

–

–

–

Percent body fat (0/1)

–

–

–

Visceral fat level (0/1)

0.69 [0.30–1.60]; 0.39

–

0.53 [0.17–1.64]; 0.27

HbA₁c (0/1)

–

–

–

IR-HOMA (0/1)

0.67 [0.21–2.14]; 0.50

–

1.02 [0.88–1.17]; 0.82

sCD36

–

–

–

Dnmt3a

0.90 [0.75–1.07]; 0.23

–

0.66 [0.32–1.37]; 0.26

Total cholesterol (0/1)

–

–

–

HD cholesterol (0/1)

6.49^e+3 [0.00–8.70^e+9]; 0.22

–

0.26 [0.00–3.99^e+3]; 0.79

LDL cholesterol (0/1)

–

–

–

Triglycerides (0/1)

0.08 [0.00–31.72]; 0.41

–

7.56 [0.24–238.49]; 0.25