Variables | Control n = 50 | Obese n = 50 | Obese diabetic n = 50 | ||||||
---|---|---|---|---|---|---|---|---|---|
rs1761667 | GG | AA/AG | p value | GG | AA/AG | p value | GG | AA/AG | p value |
Body mass index (kg/m2) | 24.58 ± 2.38 | 23.81 ± 3.05 | NS | 34.56 ± 4.14 | 34.14 ± 4.63 | NS | 34.24 ± 5.31 | 32.26 ± 3.25 | NS |
Waist size (cm) | 84.00 ± 10.19 | 82.76 ± 8.47 | NS | 102.37 ± 9.86 | 102.23 ± 10.29 | NS | 104.95 ± 14.11 | 98.86 ± 8.91 | 0.04* |
Percent body fat (%) | 39.00 ± 4.94 | 36.46 ± 7.42 | NS | 46.39 ± 4.16 | 45.88 ± 3.85 | NS | 45.50 ± 4.61 | 44.25 ± 4.53 | NS |
Visceral fat level | 7.29 ± 1.68 | 6.80 ± 1.83 | NS | 11.84 ± 2.04 | 11.35 ± 2.12 | NS | 11.71 ± 2.72 | 10.79 ± 1.92 | NS |
Glycated hemoglobin (%) | 5.08 ± 0.57 | 4.93 ± 0.39 | NS | 5.50 ± 0.59 | 5.55 ± 0.73 | NS | 8.00 ± 2.01 | 7.81 ± 2.09 | NS |
HOMAIR | 4.04 ± 1.64 | 3.32 ± 1.73 | NS | 5.20 ± 2.33 | 4.74 ± 1.81 | NS | 14.21 ± 13.15 | 10.42 ± 10.23 | NS |
Total cholesterol (g/l) | 2.23 ± 0.42 | 2.04 ± 0.45 | NS | 2.12 ± 0.43 | 2.07 ± 0.40 | NS | 2.37 ± 0.65 | 2.19 ± 0.49 | NS |
HDL cholesterol (g/l) | 0.63 ± 0.13 | 0.61 ± 0.14 | NS | 0.58 ± 0.16 | 0.58 ± 0.11 | NS | 0.64 ± 0.19 | 0.54 ± 0.12 | 0.04* |
LDL cholesterol (g/l) | 1.46 ± 0.30 | 1.34 ± 0.41 | NS | 1.38 ± 0.40 | 1.37 ± 0.41 | NS | 1.68 ± 0.60 | 1.62 ± 0.49 | NS |
Triglycerides (g/l) | 0.84 ± 0.35 | 0.76 ± 0.28 | NS | 0.86 ± 0.43 | 0.73 ± 0.24 | NS | 0.84 ± 0.36 | 0.89 ± 0.39 | NS |
rs3211867 | CC | AA/AC | p value | CC | AA/AC | p value | CC | AA/AC | p value |
Body mass index (kg/m2) | 23.46 ± 2.87 | 24.65 ± 2.59 | NS | 33.29 ± 3.50 | 35.32 ± 5.03 | 0.02* | 31.94 ± 3.51 | 33.63 ± 4.58 | NS |
Waist size (cm) | 80.95 ± 9.23 | 84.90 ± 9.13 | NS | 99.24 ± 8.72 | 105.32 ± 10.48 | NS | 100.0 ± 12.82 | 102.09 ± 11.21 | NS |
Percent body fat (%) | 35.99 ± 7.94 | 38.78 ± 5.04 | NS | 45.38 ± 3.37 | 46.78 ± 4.38 | NS | 43.71 ± 5.17 | 45.28 ± 4.23 | NS |
Visceral fat level | 6.74 ± 1.94 | 7.23 ± 1.63 | NS | 11.12 ± 1.79 | 11.96 ± 2.30 | NS | 10.19 ± 1.91 | 11.65 ± 2.36 | NS |
Glycated hemoglobin (%) | 4.86 ± 0.44 | 5.09 ± 0.50 | NS | 5.52 ± 0.80 | 5.55 ± 0.53 | NS | 7.69 ± 1.92 | 7.98 ± 2.11 | NS |
HOMA-IR | 4.01 ± 1.87 | 3.45 ± 1.60 | NS | 4.62 ± 1.96 | 5.21 ± 2.05 | NS | 11.86 ± 10.96 | 12.39 ± 10.15 | NS |
Total cholesterol (g/l) | 2.11 ± 0.48 | 2.15 ± 0.43 | NS | 2.00 ± 0.42 | 2.18 ± 0.39 | NS | 2.03 ± 0.38 | 2.37 ± 0.60 | 0.03* |
HDL cholesterol (g/l) | 0.59 ± 0.15 | 0.64 ± 0.13 | NS | 0.55 ± 0.12 | 0.61 ± 0.13 | NS | 0.54 ± 0.17 | 0.61 ± 0.16 | NS |
LDL cholesterol (g/l) | 1.45 ± 0.37 | 1.37 ± 0.37 | NS | 1.35 ± 0.41 | 1.40 ± 0.39 | NS | 1.44 ± 0.38 | 1.73 ± 0.57 | NS |
Triglycerides (g/l) | 0.73 ± 0.25 | 0.84 ± 0.34 | NS | 0.71 ± 0.28 | 0.85 ± 0.37 | NS | 0.88 ± 0.44 | 0.86 ± 0.34 | NS |
rs1527483 | GG | AA/AG | p value | GG | AA/AG | p value | GG | AA/AG | p value |
Body mass index (kg/m2) | 24.44 ± 2.51 | 18.75 ± 1.48 | 0.003** | 34.24 ± 4.44 | – | – | 33.25 ± 4.33 | 31.65 ± 1.90 | NS |
Waist size (cm) | 83.38 ± 9.14 | 75.00 ± 4.24 | NS | 102.76 ± 9.68 | – | – | 101.73 ± 11.69 | 97.50 ± 10.61 | NS |
Percent body fat (%) | 37.96 ± 6.37 | 36.60 ± 1.27 | NS | 45.78 ± 4.22 | – | – | 44.75 ± 4.65 | 44.30 ± 1.13 | NS |
Visceral fat level | 6.98 ± 1.68 | 6.00 ± 1.41 | NS | 11.53 ± 2.09 | – | – | 11.27 ± 2.32 | 9.50 ± 0.71 | NS |
Glycated hemoglobin (%) | 5.00 ± 0.50 | 4.90 ± 0.14 | NS | 5.50 ± 0.57 | – | – | 7.88 ± 2.07 | 8.65 ± 0.49 | NS |
HOMA-IR | 3.66 ± 1.83 | 2.95 ± 0.78 | NS | 4.82 ± 2.12 | – | – | 7.83 ± 11.12 | 7.42 ± 10.50 | NS |
Total cholesterol (g/l) | 2.11 ± 0.44 | 2.49 ± 0.88 | NS | 2.11 ± 0.39 | – | – | 2.25 ± 0.55 | 2.42 ± 1.03 | NS |
HDL cholesterol (g/l) | 0.62 ± 0.13 | 0.75 ± 0.16 | NS | 0.58 ± 0.13 | – | – | 0.58 ± 0.16 | 0.55 ± 0.15 | NS |
LDL cholesterol (g/l) | 1.36 ± 0.37 | 1.87 ± 0.33 | NS | 1.40 ± 0.38 | – | – | 1.63 ± 0.54 | 1.80 ± 0.48 | NS |
Triglycerides (g/l) | 0.81 ± 0.31 | 0.62 ± 1.56 | NS | 0.78 ± 0.34 | – | – | 0.85 ± 0.35 | 1.18 ± 0.71 | NS |