Skip to main content

Table 4 Comparison of the clinical and biochemical data stratified by CD36 gene polymorphisms in the control, obese and obese diabetic groups

From: Association between polymorphisms and hypermethylation of CD36 gene in obese and obese diabetic Senegalese females

Variables

Control

n = 50

Obese

n = 50

Obese diabetic

n = 50

rs1761667

GG

AA/AG

p value

GG

AA/AG

p value

GG

AA/AG

p value

 Body mass index (kg/m2)

24.58 ± 2.38

23.81 ± 3.05

NS

34.56 ± 4.14

34.14 ± 4.63

NS

34.24 ± 5.31

32.26 ± 3.25

NS

 Waist size (cm)

84.00 ± 10.19

82.76 ± 8.47

NS

102.37 ± 9.86

102.23 ± 10.29

NS

104.95 ± 14.11

98.86 ± 8.91

0.04*

 Percent body fat (%)

39.00 ± 4.94

36.46 ± 7.42

NS

46.39 ± 4.16

45.88 ± 3.85

NS

45.50 ± 4.61

44.25 ± 4.53

NS

 Visceral fat level

7.29 ± 1.68

6.80 ± 1.83

NS

11.84 ± 2.04

11.35 ± 2.12

NS

11.71 ± 2.72

10.79 ± 1.92

NS

 Glycated hemoglobin (%)

5.08 ± 0.57

4.93 ± 0.39

NS

5.50 ± 0.59

5.55 ± 0.73

NS

8.00 ± 2.01

7.81 ± 2.09

NS

 HOMAIR

4.04 ± 1.64

3.32 ± 1.73

NS

5.20 ± 2.33

4.74 ± 1.81

NS

14.21 ± 13.15

10.42 ± 10.23

NS

 Total cholesterol (g/l)

2.23 ± 0.42

2.04 ± 0.45

NS

2.12 ± 0.43

2.07 ± 0.40

NS

2.37 ± 0.65

2.19 ± 0.49

NS

 HDL cholesterol (g/l)

0.63 ± 0.13

0.61 ± 0.14

NS

0.58 ± 0.16

0.58 ± 0.11

NS

0.64 ± 0.19

0.54 ± 0.12

0.04*

 LDL cholesterol (g/l)

1.46 ± 0.30

1.34 ± 0.41

NS

1.38 ± 0.40

1.37 ± 0.41

NS

1.68 ± 0.60

1.62 ± 0.49

NS

 Triglycerides (g/l)

0.84 ± 0.35

0.76 ± 0.28

NS

0.86 ± 0.43

0.73 ± 0.24

NS

0.84 ± 0.36

0.89 ± 0.39

NS

rs3211867

CC

AA/AC

p value

CC

AA/AC

p value

CC

AA/AC

p value

 Body mass index (kg/m2)

23.46 ± 2.87

24.65 ± 2.59

NS

33.29 ± 3.50

35.32 ± 5.03

0.02*

31.94 ± 3.51

33.63 ± 4.58

NS

 Waist size (cm)

80.95 ± 9.23

84.90 ± 9.13

NS

99.24 ± 8.72

105.32 ± 10.48

NS

100.0 ± 12.82

102.09 ± 11.21

NS

 Percent body fat (%)

35.99 ± 7.94

38.78 ± 5.04

NS

45.38 ± 3.37

46.78 ± 4.38

NS

43.71 ± 5.17

45.28 ± 4.23

NS

 Visceral fat level

6.74 ± 1.94

7.23 ± 1.63

NS

11.12 ± 1.79

11.96 ± 2.30

NS

10.19 ± 1.91

11.65 ± 2.36

NS

 Glycated hemoglobin (%)

4.86 ± 0.44

5.09 ± 0.50

NS

5.52 ± 0.80

5.55 ± 0.53

NS

7.69 ± 1.92

7.98 ± 2.11

NS

 HOMA-IR

4.01 ± 1.87

3.45 ± 1.60

NS

4.62 ± 1.96

5.21 ± 2.05

NS

11.86 ± 10.96

12.39 ± 10.15

NS

 Total cholesterol (g/l)

2.11 ± 0.48

2.15 ± 0.43

NS

2.00 ± 0.42

2.18 ± 0.39

NS

2.03 ± 0.38

2.37 ± 0.60

0.03*

 HDL cholesterol (g/l)

0.59 ± 0.15

0.64 ± 0.13

NS

0.55 ± 0.12

0.61 ± 0.13

NS

0.54 ± 0.17

0.61 ± 0.16

NS

 LDL cholesterol (g/l)

1.45 ± 0.37

1.37 ± 0.37

NS

1.35 ± 0.41

1.40 ± 0.39

NS

1.44 ± 0.38

1.73 ± 0.57

NS

 Triglycerides (g/l)

0.73 ± 0.25

0.84 ± 0.34

NS

0.71 ± 0.28

0.85 ± 0.37

NS

0.88 ± 0.44

0.86 ± 0.34

NS

rs1527483

GG

AA/AG

p value

GG

AA/AG

p value

GG

AA/AG

p value

 Body mass index (kg/m2)

24.44 ± 2.51

18.75 ± 1.48

0.003**

34.24 ± 4.44

33.25 ± 4.33

31.65 ± 1.90

NS

 Waist size (cm)

83.38 ± 9.14

75.00 ± 4.24

NS

102.76 ± 9.68

101.73 ± 11.69

97.50 ± 10.61

NS

 Percent body fat (%)

37.96 ± 6.37

36.60 ± 1.27

NS

45.78 ± 4.22

44.75 ± 4.65

44.30 ± 1.13

NS

 Visceral fat level

6.98 ± 1.68

6.00 ± 1.41

NS

11.53 ± 2.09

11.27 ± 2.32

9.50 ± 0.71

NS

 Glycated hemoglobin (%)

5.00 ± 0.50

4.90 ± 0.14

NS

5.50 ± 0.57

7.88 ± 2.07

8.65 ± 0.49

NS

 HOMA-IR

3.66 ± 1.83

2.95 ± 0.78

NS

4.82 ± 2.12

7.83 ± 11.12

7.42 ± 10.50

NS

 Total cholesterol (g/l)

2.11 ± 0.44

2.49 ± 0.88

NS

2.11 ± 0.39

2.25 ± 0.55

2.42 ± 1.03

NS

 HDL cholesterol (g/l)

0.62 ± 0.13

0.75 ± 0.16

NS

0.58 ± 0.13

0.58 ± 0.16

0.55 ± 0.15

NS

 LDL cholesterol (g/l)

1.36 ± 0.37

1.87 ± 0.33

NS

1.40 ± 0.38

1.63 ± 0.54

1.80 ± 0.48

NS

 Triglycerides (g/l)

0.81 ± 0.31

0.62 ± 1.56

NS

0.78 ± 0.34

0.85 ± 0.35

1.18 ± 0.71

NS

  1. HOMA-IR Homeostasis Model Assessment-Insulin Resistance
  2. *p ≤ 0.05
  3. **p ≤ 0.01
  4. ***p ≤ 0.0001