Table 2 Comparison of clinical and biochemical characteristics between control, obese and obese diabetic groups
Variables | Control n = 50 (a) | Obese n = 50 (b) | Obese diabetic n = 50 (c) | p-value (a) vs (b) | p-value (a) vs (c) | p-value (b) vs (c) |
|---|---|---|---|---|---|---|
Mean age (years) | 49.98 ± 7.52 | 50.50 ± 8.76 | 51.06 ± 5.78 | NS | NS | NS |
Waist size (cm) | 83.37 ± 9.28 | 102.28 ± 10.02 | 101.42 ± 11.66 | < 0.0001 | < 0.0001 | NS |
Height (cm) | 166.53 ± 6.71 | 160.84 ± 7.71 | 162.70 ± 6.04 | NS | NS | NS |
Weight (kg) | 67.48 ± 9.92 | 92.87 ± 14.22 | 87.98 ± 13.39 | < 0.0001 | < 0.0001 | NS |
BMI (kg/m2) | 24.19 ± 2.74 | 34.30 ± 4.41 | 33.09 ± 4.30 | < 0.0001 | < 0.0001 | NS |
Percent body fat (%) | 37.70 ± 6.39 | 46.08 ± 3.93 | 44.98 ± 4.56 | < 0.0001 | < 0.0001 | NS |
Visceral fat level | 7.04 ± 1.76 | 11.54 ± 2.08 | 11.18 ± 2.31 | < 0.0001 | < 0.0001 | NS |
Glycated hemoglobin (%) | 5.00 ± 1.76 | 5.57 ± 0.69 | 7.93 ± 2.07 | 0.047 | < 0.0001 | < 0.0001 |
Fasting blood glucose (g/L) | 0.85 ± 0.13 | 0.85 ± 0.18 | 1.57 ± 0.78 | NS | < 0.0001 | < 0.0001 |
Fasting Insulin (µUI/mL) | 17.53 ± 6.29 | 23.49 ± 7.45 | 31.45 ± 25.10 | 0.036 | < 0.0001 | 0.01 |
HOMA-IR | 3.66 ± 1.71 | 4.91 ± 2.01 | 12.19 ± 11.65 | NS | 0.002 | 0.02 |
Total Cholesterol (g/L) | 2.13 ± 0.44 | 2.09 ± 0.41 | 2.27 ± 0.56 | NS | NS | NS |
HDL Cholesterol (g/L) | 0.62 ± 0.14 | 0.58 ± 0.13 | 0.58 ± 0.16 | NS | NS | NS |
LDL Cholesterol (g/L) | 1.40 ± 0.37 | 1.37 ± 0.40 | 1.64 ± 0.53 | NS | 0.004 | 0.009 |
Triglycerides (g/L) | 0.80 ± 0.31 | 0.78 ± 0.33 | 0.86 ± 0.37 | NS | NS | NS |
ALT (UI/L) | 17.57 ± 11.08 | 17.34 ± 8.88 | 19.68 ± 9.62 | NS | NS | NS |
AST (UI/L) | 24.66 ± 1388 | 21.60 ± 8.00 | 24.16 ± 8.88 | NS | NS | NS |
Albuminemia (g/L) | 44.76 ± 4.36 | 41.90 ± 4.85 | 42.82 ± 5.50 | 0.03 | NS | NS |
Bilirubinemia (g/L) | 3.98 ± 2.19 | 5.54 ± 12.09 | 5.00 ± 3.49 | NS | NS | NS |
Creatinine (g/L) | 8.87 ± 3.13 | 9.02 ± 2.79 | 10.59 ± 14.01 | NS | NS | NS |