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Fig. 4 | Diabetology & Metabolic Syndrome

Fig. 4

From: MiR-574-3p inhibits glucose toxicity-induced pancreatic β-cell dysfunction by suppressing PRMT1

Fig. 4

miR-574-3p suppresses PRMT1 expression in pancreatic β-cells. A Potential target genes of the miR-574-3p as predicted. B miR-574-3p mimic was transfected into MIN6 cells. Cell lysates were subjected to RT-qPCR analysis. C A luciferase reporter assay was used to detect the luciferase activity of WT or MUT 3′UTR PRMT1 in MIN6 cells transfected with miRNA mimics or NC. D RT-qPCR analysis determined the PRMT1 mRNA levels in MIN6 cells cotransfected with miRNA mimics, miRNA inhibitor, or NC. **P < 0.01 vs. NC 

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