Oral glucose tolerance testing at 1 h and 2 h: relationship with glucose and cardiometabolic parameters and agreement for pre-diabetes diagnosis in patients with morbid obesity

Table 3 Correlations between 1 and 2hPG and glucose and cardiometabolic parameter

Parameter	Fasting glucose		1hPG		2hPG
	Correlation coefficient*	p-value	Correlation coefficient*	p-value	Correlation coefficient*	p-value
Fasting glucose (mg/dL)	−	–	0.581	< 0.001	0.359	< 0.001
HOMA-β	−0.310^†	< 0.001	−0.092^†	0.018	0.029^†	0.462
HOMA-IR	0.312^†	< 0.001	0.281^†	< 0.001	0.254^†	< 0.001
HbA1c (%)	0.354	< 0.001	0.347	< 0.001	0.221	< 0.001
Peptide C (ng/mL)	0.293	< 0.001	0.315	< 0.001	0.238	< 0.001
Triglyceride (mg/dL)	0.093^†	0.018	0.247^†	< 0.001	0.226^†	< 0.001
HDL-cholesterol (mg/dL)	−0.093	0.018	−0.099	0.012	−0.041	0.300
LDL-cholesterol (mg/dL)	0.047	0.234	0.043	0.286	0.043	0.283
Total-cholesterol (mg/dL)	0.039	0.326	0.069	0.078	0.078	0.047
hsCRP (mg/dL)	−0.037^†	0.430	0.061^†	0.186	0.192^†	< 0.001
Creatinine (mg/dL)	−0.027^†	0.502	−0.018^†	0.652	−0.061^†	0.126
Insulinogenic index	−0.255^†	< 0.001	−0.391^†	< 0.001	−0.259^†	< 0.001
SBP (mmHg)	0.147	< 0.001	0.138	0.002	0.106	0.015
DBP (mmHg)	0.110	0.012	0.077	0.080	0.038	0.386

1hPG 1-h plasma glucose concentration, 2hPG 2-h plasma glucose concentration, DBP Diastolic blood pressure, HbA1c glycated haemoglobin, HDL-c high-density lipoprotein cholesterol, HOMA-β homeostatic model assessment for cell-β function, HOMA-IR homeostatic model assessment for insulin resistance, hsCRP high sensitivity C-reactive protein, LDL-c low-density lipoprotein cholesterol, PG post-load glucose, SBP Systolic blood pressure
*Pearson correlation coefficient, or otherwise specified
^†Spearman correlation coefficient

ISSN: 1758-5996