Skip to main content
Fig. 5 | Diabetology & Metabolic Syndrome

Fig. 5

From: Targeting ferroptosis with miR-144-3p to attenuate pancreatic β cells dysfunction via regulating USP22/SIRT1 in type 2 diabetes

Fig. 5

Anti-hyperglycemic effect of miR-144-3p antagomir in the T2DM mouse model. The serum A glucose and B insulin levels were detected using the corresponding detection kits. C The homeostasis model assessment of pancreatic β-cells, (HOMA-β) = 20 × fasting insulin/ (fasting blood glucose-3.5). D Representative images of hematoxylin and eosin (H&E) staining for the pancreas from diverse groups. E The levels of SIRT1, USP22, and ferroptosis-related proteins (GPX4 and TFR1) were evaluated by western blot (*P < 0.05, **P < 0.01, and ***P < 0.005)

Back to article page

Diabetology & Metabolic Syndrome

ISSN: 1758-5996

Contact us