Fig. 1

Evaluation of ferroptosis in the pancreas of T2DM mouse model. Pancreatic tissues were collected from T2DM mouse models (n = 8) as well as from normal mice (n = 8). A Serum glucose levels, B pancreatic GSH content, C pancreatic SOD activity, D pancreatic MDA levels, and E serum iron content were measured using the corresponding detection kits. F The expression of miR-144-3p in pancreatic tissues between the control and T2DM model groups. The correlations of miR-144-3p expression with G GSH content, H MDA levels, I SOD activity, and J serum iron content were evaluated using Person correlation coefficient (***P < 0.005)