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Fig. 1 | Diabetology & Metabolic Syndrome

Fig. 1

From: LncRNA MCM3AP-AS1 is downregulated in diabetic retinopathy and promotes cell apoptosis by regulating miR-211/SIRT1

Fig. 1

MCM3AP-AS1 was downregulated in DR patients and downregulated by high D-glucose in ARPE-19 cells. Plasma levels of MCM3AP-AS1 in DR patients (n = 80), T2DM patients (n = 80), and Controls (n = 80) were measured by qPCR, and data comparisons were performed using ANOVA (one-way) and Tukey test (A). ARPE-19 cells were cultured in a medium containing 5, 15, 30, and 50 nM D-glucose for 24 h, followed by the measurement of MCM3AP-AS1 expression levels using qPCR (B). PCR reactions were repeated 3 times, and mean values were presented. *p < 0.05

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