| Model 1a | Model 2b | P-value | Model 3c | P-value |
---|
HR (95% CI) | P-value | HR (95% CI) | HR (95% CI) |
---|
No comorbidity | 1.0 (ref.) | Â | 1.0 | Â | 1.0 | Â |
Low HDL-C | 0.76 (0.58, 0.98) | 0.037 | 0.74 (0.56, 0.97) | 0.032 | 1.07 (0.63, 1.83) | 0.787 |
DM | 1.43 (0.97, 2.11) | 0.072 | 1.32 (0.86, 2.01) | 0.202 | 1.83 (0.98, 3.41) | 0.057 |
DM plus low HDL-C | 1.86 (1.25, 2.76) | 0.002 | 1.69 (1.09, 2.62) | 0.020 | 2.81 (1.32, 4.73) | 0.005 |
- Statistically significant results are indicated in bold
- HR hazard ratio, CI confidence interval, HDL-C high-density lipoprotein cholesterol, DM diabetes mellitus
- aUnadjusted
- bModel 1 plus age, sex, body mass index, current smoking, pre-existing stroke, pre-existing cardiovascular disease
- cModel 2 plus hemoglobin, serum albumin, cholesterol, triglyceride, low-density lipoprotein, intact parathyroid hormone, statins and serum potassium