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Table 3 Association of baseline and change in HbA1c with changes in SBP and DBP

From: Associations of the baseline level and change in glycosylated hemoglobin A1c with incident hypertension in non-diabetic individuals: a 3-year cohort study

 

Change in SBP

Change in DBP*

β-coefficient (95% CI)

p value

β-coefficient (95% CI)

p value

Baseline HbA1c

    

Unadjusted

1.971 (0.105–3.837)

0.038

0.984 (− 0.184–2.152)

0.099

Model 1

− 0.538 (− 2.340–1.265)

0.599

0.246 (− 0.877–1.369)

0.668

Model 2

− 0.042 (− 0.617–1.032)

0.881

− 0.168 (− 1.035–0.699)

0.704

Model 3

− 0.023 (− 1.501–1.455)

0.976

− 0.243 (− 1.103–0.617)

0.580

Change in HbA1c

    

Unadjusted

5.528 (3.415–7.642)

 < 0.001

2.328 (1.005–3.651)

0.001

Model 1

4.996 (3.033–6.958)

 < 0.001

1.978 (0.753–3.204)

0.002

Model 2

5.020 (3.528–6.512)

 < 0.001

1.830 (0.919–2.742)

 < 0.001

Model 3

4.473 (2.989–5.957)

 < 0.001

1.527 (0.619–2.436)

0.001

Model 4

4.421 (2.811–6.032)

 < 0.001

1.681 (0.695–2.667)

0.001

  1. Data are β-coefficients of linear regression (95% confidence interval). Model 1: adjusted for age (continuous), sex, education level, current smoking, and current alcohol consumption; Model 2: Model 1 + body mass index, fasting plasma glucose, total cholesterol, triglycerides, high-density lipoprotein cholesterol, and SBP at baseline (all continuous); Model 3: Model 2 + change in body mass index (continuous); Model 4: Model 3 + HbA1c at baseline (continuous). * In Models 2–4 with change in DBP as the dependent variable, DBP at baseline instead of SBP at baseline was adjusted. CI confidence interval; HbA1c glycated hemoglobin A1c; SBP systolic blood pressure; DBP diastolic blood pressure
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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