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Table 4 Association of CIMT and FIMT with UAE and eGFR

From: Albuminuria but not low eGFR is closely associated with atherosclerosis in patients with type 2 diabetes: an observational study

  UAE eGFR
β (95% CI) p values β (95% CI) p values
CIMT
 Model 1 0.10 (0.06–0.14)  < 0.001 − 0.23 (-0.27-0.20)  < 0.001
 Model 2 0.07 (0.04–0.11)  < 0.001 − 0.02 (-0.06–0.03) 0.461
 Model 3 0.07 (0.03–0.10)  < 0.001 − 0.01 (-0.05–0.03) 0.486
 Model 4 0.05 (0.02–0.09) 0.006 − 0.01 (-0.05–0.03) 0.660
 Model 5 0.05 (0.01–0.09) 0.029 − 0.01 (-0.05–0.04) 0.701
FIMT
 Model 1 0.10 (0.06–0.14)  < 0.001 − 0.27 (-0.31-0.23)  < 0.001
 Model 2 0.08 (0.04–0.11)  < 0.001 − 0.04 (-0.08–0.00) 0.053
 Model 3 0.07 (0.04–0.11)  < 0.001 − 0.04 (-0.08–0.00) 0.052
 Model 4 0.08 (0.04–0.12)  < 0.001 − 0.04 (-0.08–0.00) 0.070
 Model 5 0.07 (0.03–0.11) 0.001 − 0.04 (-0.08–0.01) 0.134
  1. UAE urinary albumin excretion, eGFR estimated glomerular filtration rate, DD duration of diabetes, APA anti-platelet agents, LLD lipid-lowering drugs, AHA anti-hypertensive agents, SBP systolic blood pressure, DBP diastolic blood pressure, WC waist circumference, WHR waist-to-hip ratio, BMI body mass index, FPG fasting plasma glucose, 2-h PPG 2-h postprandial plasma glucose, HbA1c glycated hemoglobin A1c, FCP fasting C-peptide, 2-h PCP 2-h postprandial C-peptide, HOMA2-IR HOMA of insulin resistance, TG total triglycerides, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ALT alanine transaminase, SUA serum uric acid
  2. Model 1: unadjusted
  3. Model 2: Adjusted for age, sex, DD, hypertension, smoking status and alcohol use
  4. Model 3: Further adjustment for use of AHA, LLD, APA
  5. Model 4: Further adjustment for SBP, DBP, BMI, WC and WHR
  6. Model 5: Further adjustment for ALT, TG, TC, HDL-C, LDL-C, SUA, FPG, 2-h PPG, HbA1c, FCP, 2-h PCP, HOMA2-IR