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Table 2 Clinical and laboratory parameters of patients with T1DM before and after vitamin D supplementation

From: Health-related quality of life in T1DM patients after high-dose cholecalciferol supplementation: data from a pilot clinical trial

Parameters (N = 64)

Pre VD

Post VD

P

BMI (kg/m2)

24 ± 4

24 ± 4

NS (0.247)

Systolic Blood Pressure (mmHg)

115 ± 11

115 ± 12

NS (0.765)

Diastolic Blood Pressure (mmHg)

71 ± 9

72 ± 9

NS (0.153)

Basal insulin dose (IU)

35.6 ± 17

36 ± 18

NS (0.957)

Prandial insulin dose (IU)

22.3 ± 12

23.3 ± 12

NS (0.177)

Total insulin dose (IU)

55.8 ± 27

58.1 ± 27

NS (0.708)

25(OH)VD (ng/mL)

26.7 ± 9

55.1 ± 24

 < 0.001

HbA1c (%)

9.6 ± 2

9.8 ± 3

NS (0.250)

Fasting plasma glucose (mg/dL)

168 ± 96

180.6 ± 103

NS (0.497)

Ultrasensible CRP (mg/L)

0.36 ± 0.52

0.37 ± 0.54

NS (0.727)

Total cholesterol (mg/dL)

171.7 ± 41

177 ± 54

NS (0.292)

HDL cholesterol (mg/dL)

52 ± 38

44.6 ± 11

NS (0.293)

LDL cholesterol (mg/dL)

103.7 ± 31

107.9 ± 49

NS (0.714)

Non-HDL cholesterol (mg/dL)

123.5 ± 38

125.7 ± 50

NS (0.289)

Triglycerides (mg/dL)

97.7 ± 51

109.6 ± 70

NS (0.186)

  1. IU international units, NS non significant, BMI body-mass index, HbA1c glycated hemoglobin, CRP c-reactive protein, GFR glomerular filtration rate, HDL high-density lipoprotein, LDL low-density lipoprotein