Glucose-6-Phosphate dehydrogenase deficiency associated hemolysis in a cohort of new onset type 1 diabetes children in Guangdong province, China

Table 4 Pathogenic mutations and their descriptions of 18 type 1 diabetes with G6PD deficiency patients

Patient	Age at onset	Gender	G6PD gene					G6PD/6PGD
Patient	Age at onset	Gender	Mutation name	Exon	Nucleotide change	Amino acid change	Genotype	G6PD/6PGD
1	9y	F	Kaiping	12	c.1388G > A	p.Arg493His	Homo	0.12
2	2y8m	M	Canton	11	c.1376G > T	p.Arg459Leu	Hemi	0.10
3	3y	M	Gaohe	2	c.95A > G	p.His32Arg	Hemi	0.12
5	1y8m	M	Kaiping	12	c.1388G > A	p.Arg493His	Hemi	0.06
6	12y	M	Canton	11	c.1376G > T	p.Arg459Leu	Hemi	0.09
7	11y	M	Kaiping	12	c.1388G > A	p.Arg493His	Hemi	0.12
8	16y	M	Gaohe	2	c.95A > G	p.His32Arg	Hemi	0.12
9	10 m	M	Gaohe	2	c.95A > G	p.His32Arg	Hemi	0.88
10	2y3m	M	Gaohe	2	c.95A > G	p.His32Arg	Hemi	0.06
11	3y	F	Kaiping	12	c.1388G > A	p.Arg493His	Homo	0.26
12	13y10m	F	Kaiping	12	c.1388G > A	p.Arg493His	Homo	0.34
13	7y	F	Canton	11	c.1376G > T	p.Arg459Leu	Hetero	0.94
14	1y2m	M	Kaiping	12	c.1388G > A	p.Arg493His	Hemi	0.09
15	7y	M	Canton	11	c.1376G > T	p.Arg459Leu	Hemi	0.39
16	7y	M	Canton	11	c.1376G > T	p.Arg459Leu	Hemi	0.09
17	5y	M	Viangchan	9	c.871G > A	p.Val291Met	Hemi	0.77
18	9y	F	Canton	11	c.1376G > T	p.Arg459Leu	Homo	0.28
19	11 m	M	Canton	11	c.1376G > T	p.Arg459Leu	Hemi	0.16

ISSN: 1758-5996